Anti-VAPA Antibody (CAB12939)
- SKU:
- CAB12939
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-VAPA Antibody |
| 抗体コード: | CAB12939 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 137-227 of human VAPA (NP_919415.2). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | B-cell, Mouse heart, Mouse pancreas |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 137-227 of human VAPA (NP_919415.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DKLN DMEP SKAV PLNA SKQD GPMP KPHS VSLN DTET RKLM EECK RLQG EMMK LSEE NRHL RDEG LRLR KVAH SDKP GSTS TASF RDNV TSP |
| 遺伝子ID: | 9218 |
| Uniprot: | Q9P0L0 |
| セルラーロケーション: | Endoplasmic reticulum membrane, Single-pass type IV membrane protein |
| 計算された分子量: | 27kDa/32kDa |
| 観察された分子量: | 28kDa |
| 同義語: | VAPA, VAP-33, VAP-A, VAP33, hVAP-33 |
| バックグラウンド: | The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. |
| UniProt Protein Function: | VAPA: May play a role in vesicle trafficking. Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Endoplasmic reticulum; Membrane protein, integral Chromosomal Location of Human Ortholog: 18p11.22 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; perinuclear region of cytoplasm; plasma membrane; tight junction; vesicle Molecular Function:FFAT motif binding; microtubule binding; protein binding; protein domain specific binding; protein heterodimerization activity; signal transducer activity Biological Process: cell death; endoplasmic reticulum organization and biogenesis; ER to Golgi vesicle-mediated transport; neurite development; positive regulation of I-kappaB kinase/NF-kappaB cascade; sphingolipid biosynthetic process |
| NCBI Summary: | The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9P0L0 |
| NCBI GenInfo Identifier: | 122066680 |
| NCBI Gene ID: | 9218 |
| NCBI Accession: | Q9P0L0.3 |
| UniProt Secondary Accession: | Q9P0L0,O75453, Q5U0E7, Q9UBZ2, A6NDZ0, D3DUI3, |
| UniProt Related Accession: | Q9P0L0 |
| Molecular Weight: | 32,614 Da |
| NCBI Full Name: | Vesicle-associated membrane protein-associated protein A |
| NCBI Synonym Full Names: | VAMP associated protein A |
| NCBI Official Symbol: | VAPA |
| NCBI Official Synonym Symbols: | VAP-A; VAP33; VAP-33; hVAP-33 |
| NCBI Protein Information: | vesicle-associated membrane protein-associated protein A |
| UniProt Protein Name: | Vesicle-associated membrane protein-associated protein A |
| UniProt Synonym Protein Names: | 33 kDa VAMP-associated protein; VAP-33 |
| Protein Family: | Virulence-associated protein |
| UniProt Gene Name: | VAPA |
| UniProt Entry Name: | VAPA_HUMAN |
 | Western blot analysis of extracts of various cell lines, using VAPA Antibody (CAB12939) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human stomach using VAPA antibody (CAB12939) at dilution of 1:100 (40x lens). |
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