Anti-UQCC2 Antibody (CAB19955)[KO Validated]

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SKU:
CAB19955
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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Description

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抗体名:Anti-UQCC2 Antibody [KO Validated]
抗体コード:CAB19955
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IHC IF
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant protein of human UQCC2.
申し込み:WB IHC IF
推奨希釈:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
反応性:Human, Mouse, Rat
ポジティブサンプル:293T
免疫原:Recombinant protein of human UQCC2.
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:84300
Uniprot:Q9BRT2
セルラーロケーション:Mitochondrion, Mitochondrion inner membrane, Mitochondrion intermembrane space, Mitochondrion matrix, mitochondrion nucleoid
計算された分子量:14kDa
観察された分子量:15KDa
Anti-UQCC2 Antibody [KO Validated] (CAB19955)Western blot analysis of extracts from normal (control) and UQCC2 knockout (KO) 293T cells, using UQCC2 antibody (CAB19955) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
同義語:UQCC2, C6orf125, C6orf126, Cbp6, M19, MNF1, bA6B20.2
バックグラウンド:This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity.
UniProt Protein Function:UQCC2: Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells
UniProt Protein Details:

Protein type:Mitochondrial

Chromosomal Location of Human Ortholog: 6p21.31

Cellular Component: mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial matrix; mitochondrion; nuclear body

Molecular Function:protein binding

Biological Process: regulation of insulin secretion; regulation of oxidative phosphorylation

Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 7

NCBI Summary:This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity. [provided by RefSeq, Oct 2012]
UniProt Code:Q9BRT2
NCBI GenInfo Identifier:73917719
NCBI Gene ID:84300
NCBI Accession:Q9BRT2.1
UniProt Secondary Accession:Q9BRT2,B2R4I0,
UniProt Related Accession:Q9BRT2
Molecular Weight:15kDa
NCBI Full Name:Ubiquinol-cytochrome-c reductase complex assembly factor 2
NCBI Synonym Full Names:ubiquinol-cytochrome c reductase complex assembly factor 2
NCBI Official Symbol:UQCC2  
NCBI Official Synonym Symbols:M19; Cbp6; MNF1; C6orf125; C6orf126; bA6B20.2  
NCBI Protein Information:ubiquinol-cytochrome-c reductase complex assembly factor 2
UniProt Protein Name:Ubiquinol-cytochrome-c reductase complex assembly factor 2
UniProt Synonym Protein Names:Breast cancer-associated protein SGA-81M; Mitochondrial nucleoid factor 1; Mitochondrial protein M19
Protein Family:Ubiquinol-cytochrome-c reductase complex assembly factor
UniProt Gene Name:UQCC2  
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