Anti-UNG Antibody (CAB13155)
- SKU:
- CAB13155
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-UNG Antibody |
抗体コード: | CAB13155 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UNG (NP_550433.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse skeletal muscle, Mouse heart, Rat skeletal muscle |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UNG (NP_550433.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MIGQ KTLY SFFS PSPA RKRH APSP EPAV QGTG VAGV PEES GDAA AIPA KKAP AGQE EPGT PPSS PLSA EQLD RIQR NKAA ALLR LAAR NVPV GFGE SWKK |
遺伝子ID: | 7374 |
Uniprot: | P13051 |
セルラーロケーション: | Mitochondrion, Nucleus |
計算された分子量: | 33kDa/34kDa |
観察された分子量: | 38kDa |
同義語: | UNG, DGU, HIGM4, HIGM5, UDG, UNG1, UNG15, UNG2 |
バックグラウンド: | This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. |
UniProt Protein Function: | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. |
NCBI Summary: | This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010] |
UniProt Code: | P13051 |
NCBI GenInfo Identifier: | 6224979 |
NCBI Gene ID: | 7374 |
NCBI Accession: | NP_003353.1 |
UniProt Secondary Accession: | P13051,O00637, O00719, Q93028, A8K5M6, B2R8Y1, |
UniProt Related Accession: | P13051 |
Molecular Weight: | |
NCBI Full Name: | uracil-DNA glycosylase isoform UNG1 |
NCBI Synonym Full Names: | uracil DNA glycosylase |
NCBI Official Symbol: | UNG |
NCBI Official Synonym Symbols: | DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15 |
NCBI Protein Information: | uracil-DNA glycosylase |
UniProt Protein Name: | Uracil-DNA glycosylase |
Protein Family: | Probable uracil-DNA glycosylase |
UniProt Gene Name: | UNG |
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