Anti-UNC5A Antibody (CAB18521)
- SKU:
- CAB18521
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-UNC5A Antibody |
| 抗体コード: | CAB18521 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human UNC5A. |
| 申し込み: | IF |
| 推奨希釈: | IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant protein of human UNC5A. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 90249 |
| Uniprot: | Q6ZN44 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | Refer to figures |
| 同義語: | UNC5H1, UNC5A |
| バックグラウンド: |
| UniProt Protein Function: | UNC5A: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Belongs to the unc-5 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cell development/differentiation; Membrane protein, integral Chromosomal Location of Human Ortholog: 5q35.2 Cellular Component: integral to membrane; intrinsic to plasma membrane; lipid raft; plasma membrane Biological Process: anterior/posterior axon guidance; apoptosis; axon guidance; neurite development; programmed cell death |
| NCBI Summary: | UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q6ZN44 |
| NCBI GenInfo Identifier: | 296453000 |
| NCBI Gene ID: | 90249 |
| NCBI Accession: | Q6ZN44.3 |
| UniProt Related Accession: | Q6ZN44 |
| Molecular Weight: | |
| NCBI Full Name: | Netrin receptor UNC5A |
| NCBI Synonym Full Names: | unc-5 netrin receptor A |
| NCBI Official Symbol: | UNC5A |
| NCBI Official Synonym Symbols: | UNC5H1 |
| NCBI Protein Information: | netrin receptor UNC5A |
| UniProt Protein Name: | Netrin receptor UNC5A |
| UniProt Synonym Protein Names: | Protein unc-5 homolog 1; Protein unc-5 homolog A |
| Protein Family: | Netrin receptor |
| UniProt Gene Name: | UNC5A |
| UniProt Entry Name: | UNC5A_HUMAN |