Anti-UCKL1 Antibody (CAB15851)
- SKU:
- CAB15851
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-UCKL1 Antibody |
| 抗体コード: | CAB15851 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human UCKL1 (NP_060329.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse heart, Mouse lung, Rat pancreas |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human UCKL1 (NP_060329.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAAP PARA DADP SPTS PPTA RDTP GRQA EKSE TACE DRSN AESL DRLL PPVG TGRS PRKR TTSQ CKSE PPLL RTSK RTIY TAGR PPWY NEHG TQSK EAFA IGLG GGSA SGKT TVAR MIIE ALDV PWVV LLSM DSFY KVLT EQQQ EQAA HNNF NFDH PDAF DFDL IIST LKKL KQGK SVKV PIYD FTTH SRKK DWKT LYGA |
| 遺伝子ID: | 54963 |
| Uniprot: | Q9NWZ5 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 44kDa/45kDa/59kDa/61kDa |
| 観察された分子量: | 61kDa |
| 同義語: | UCKL1, UCK1L, URKL1 |
| バックグラウンド: | The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | UCKL1: May contribute to UTP accumulation needed for blast transformation and proliferation. Belongs to the uridine kinase family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleotide Metabolism - pyrimidine; EC 2.7.1.48; Xenobiotic Metabolism - drug metabolism - other enzymes; Transferase Chromosomal Location of Human Ortholog: 20q13.33 Cellular Component: cytoplasm; nucleus Molecular Function:protein binding; uridine kinase activity; ATP binding Biological Process: viral reproduction; phosphorylation |
| NCBI Summary: | The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] |
| UniProt Code: | Q9NWZ5 |
| NCBI GenInfo Identifier: | 84029407 |
| NCBI Gene ID: | 54963 |
| NCBI Accession: | Q9NWZ5.2 |
| UniProt Secondary Accession: | Q9NWZ5,Q5JWV0, Q70AQ5, Q8N524, Q9H3Z2, B7Z8N2, |
| UniProt Related Accession: | Q9NWZ5 |
| Molecular Weight: | 548 |
| NCBI Full Name: | Uridine-cytidine kinase-like 1 |
| NCBI Synonym Full Names: | uridine-cytidine kinase 1-like 1 |
| NCBI Official Symbol: | UCKL1 |
| NCBI Official Synonym Symbols: | UCK1L; URKL1 |
| NCBI Protein Information: | uridine-cytidine kinase-like 1; UCK1-LIKE |
| UniProt Protein Name: | Uridine-cytidine kinase-like 1 |
| Protein Family: | Uridine-cytidine kinase |
| UniProt Gene Name: | UCKL1 |
| UniProt Entry Name: | UCKL1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using UCKL1 antibody (CAB15851) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded Human breast cancer using UCKL1 Rabbit pAb (CAB15851) at dilution of 1:100 (40x lens). |
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