Anti-UAP1 Antibody (CAB2119)

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SKU:
CAB2119
Product type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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Description

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抗体名:Anti-UAP1 Antibody
抗体コード:CAB2119
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human UAP1 (NP_003106.3).
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human, Rat
ポジティブサンプル:HepG2, HT-29
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human UAP1 (NP_003106.3).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:MNIN DLKL TLSK AGQE HLLR FWNE LEEA QQVE LYAE LQAM NFEE LNFF FQKA IEGF NQSS HQKN VDAR MEPV PREV LGSA TRDQ DQLQ AWES EGLF QISQ NKVA VLLL AGGQ GTRL GVAY PKGM YDVG LPSR KTLF QIQA ERIL KLQQ VAEK YYGN KCII PWYI MTSG RTME STKE FFTK HKYF GLKK ENVI FFQQ GMLP AMSF DGKI ILEE KNKV SMAP DGNG GLYR ALAA QNIV EDME QRGI WSIH VYCV DNIL VKVA DPRF IGFC IQKG ADCG AKVV EKTN PTEP VG
遺伝子ID:6675
Uniprot:Q16222
セルラーロケーション:Cytoplasm
計算された分子量:57kDa/58kDa
観察された分子量:59kDa
同義語:UAP1, AGX, AGX1, AGX2, SPAG2
バックグラウンド:
UniProt Protein Function:UAP1: Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P. Belongs to the UDPGP type 1 family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Transferase; EC 2.7.7.23; EC 2.7.7.83; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; cytosol

Molecular Function:UDP-N-acetylglucosamine diphosphorylase activity; carbohydrate binding

Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; UDP-N-acetylglucosamine biosynthetic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification

UniProt Code:Q16222
NCBI GenInfo Identifier:68846235
NCBI Gene ID:6675
NCBI Accession:Q16222.3
UniProt Secondary Accession:Q16222,Q91YN5,
UniProt Related Accession:Q16222
Molecular Weight:
NCBI Full Name:UDP-N-acetylhexosamine pyrophosphorylase
NCBI Synonym Full Names:UDP-N-acetylglucosamine pyrophosphorylase 1
NCBI Official Symbol:UAP1  
NCBI Official Synonym Symbols:AGX; AGX1; AGX2; SPAG2  
NCBI Protein Information:UDP-N-acetylhexosamine pyrophosphorylase
UniProt Protein Name:UDP-N-acetylhexosamine pyrophosphorylase
UniProt Synonym Protein Names:Antigen X; AGX; Sperm-associated antigen 2Including the following 2 domains:UDP-N-acetylgalactosamine pyrophosphorylase (EC:2.7.7.83)Alternative name(s):AGX-1
Protein Family:UDP-N-acetylhexosamine pyrophosphorylase
UniProt Gene Name:UAP1  
UniProt Entry Name:UAP1_HUMAN
Anti-UAP1 Antibody (CAB2119)Western blot analysis of extracts of various cell lines, using UAP1 antibody (CAB2119) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min.
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