Anti-TXNL4A Antibody (CAB10138)
- SKU:
- CAB10138
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-TXNL4A Antibody |
| 抗体コード: | CAB10138 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human TXNL4A (NP_006692.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | LO2, HeLa, Jurkat, HL-60, Mouse pancreas, Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human TXNL4A (NP_006692.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSYM LPHL HNGW QVDQ AILS EEDR VVVI RFGH DWDP TCMK MDEV LYSI AEKV KNFA VIYL VDIT EVPD FNKM YELY DPCT VMFF FRNK HIMI DLGT GNNN KINW AMED KQEM VDII ETVY RGAR KGRG LVVS PKDY STKY RY |
| 遺伝子ID: | 10907 |
| Uniprot: | P83876 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 16kDa |
| 観察された分子量: | 13kDa |
| 同義語: | TXNL4A, BMKS, DIB1, DIM1, SNRNP15, TXNL4, U5-15kD |
| バックグラウンド: | The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1). Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants. |
| NCBI Summary: | The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1). Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015] |
| UniProt Code: | P83876 |
| NCBI GenInfo Identifier: | 33875918 |
| NCBI Gene ID: | 10907 |
| NCBI Accession: | BC001046 |
| UniProt Secondary Accession: | P83876,O14834, B2RC18, |
| UniProt Related Accession: | P83876 |
| Molecular Weight: | 16,786 Da |
| NCBI Full Name: | Homo sapiens thioredoxin-like 4A, mRNA |
| NCBI Synonym Full Names: | thioredoxin like 4A |
| NCBI Official Symbol: | TXNL4A |
| NCBI Official Synonym Symbols: | BMKS; DIB1; DIM1; TXNL4; SNRNP15; U5-15kD |
| NCBI Protein Information: | thioredoxin-like protein 4A |
| UniProt Protein Name: | |
| Protein Family: | Thioredoxin-like protein |
| UniProt Gene Name: |
 | Western blot analysis of extracts of various cell lines, using TXNL4A antibody (CAB10138) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |