Anti-TWF2 Antibody (CAB13642)
- SKU:
- CAB13642
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TWF2 Antibody |
| 抗体コード: | CAB13642 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IP |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human TWF2 (NP_009215.1). |
| 申し込み: | WB IHC IP |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IP 1:20 - 1:50 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Jurkat, 293T, A-431, Mouse heart, Mouse thymus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human TWF2 (NP_009215.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAHQ TGIH ATEE LKEF FAKA RAGS VRLI KVVI EDEQ LVLG ASQE PVGR WDQD YDRA VLPL LDAQ QPCY LLYR LDSQ NAQG FEWL FLAW SPDN SPVR LKML YAAT RATV KKEF GGGH IKDE LFGT VKDD LSFA GYQK HLSS CAAP APLT SAER ELQQ IRIN EVKT EISV ESKH QTLQ GLAF PLQP EAQR ALQQ LKQK MVNY IQMK LDLE RETI ELVH TEPT DVAQ LPSR VPRD AARY HFFL YKHT HEGD PLES VVFI YSMP GYKC SIKE RMLY SSCK SRLL DSVE QDFH LEIA KKIE IGDG AELT AEFL YDEV HPKQ HAFK QAFA KPKG PGGK RGHK RLIR GPGE NGDD S |
| 遺伝子ID: | 11344 |
| Uniprot: | Q6IBS0 |
| セルラーロケーション: | Cell projection, Cytoplasm, cytoskeleton, perinuclear region, stereocilium |
| 計算された分子量: | 39kDa |
| 観察された分子量: | 40kDa |
| 同義語: | TWF2, A6RP, A6r, MSTP011, PTK9L |
| バックグラウンド: | The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein. |
| UniProt Protein Function: | A6r: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia. Belongs to the actin-binding proteins ADF family. Twinfilin subfamily. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 3p21.1 Cellular Component: stereocilium; cytoskeleton; growth cone; myofibril; lamellipodium; perinuclear region of cytoplasm; cytoplasm; filopodium Molecular Function:actin monomer binding; phosphatidylinositol-4,5-bisphosphate binding; protein kinase C binding; ATP binding Biological Process: cell projection organization and biogenesis; sequestering of actin monomers; negative regulation of actin filament polymerization; regulation of actin cytoskeleton organization and biogenesis; positive regulation of axon extension; regulation of microvillus length; barbed-end actin filament capping |
| NCBI Summary: | The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q6IBS0 |
| NCBI GenInfo Identifier: | 94730596 |
| NCBI Gene ID: | 11344 |
| NCBI Accession: | Q6IBS0.2 |
| UniProt Secondary Accession: | Q6IBS0,Q9Y3F5, |
| UniProt Related Accession: | Q6IBS0 |
| Molecular Weight: | 349 |
| NCBI Full Name: | Twinfilin-2 |
| NCBI Synonym Full Names: | twinfilin actin-binding protein 2 |
| NCBI Official Symbol: | TWF2 |
| NCBI Official Synonym Symbols: | A6r; A6RP; PTK9L; MSTP011 |
| NCBI Protein Information: | twinfilin-2; A6-related protein; twinfilin-1-like protein; twinfilin, actin-binding protein, homolog 2; protein tyrosine kinase 9-like (A6-related protein); PTK9L protein tyrosine kinase 9-like (A6-related protein) |
| UniProt Protein Name: | Twinfilin-2 |
| UniProt Synonym Protein Names: | A6-related protein; hA6RP; Protein tyrosine kinase 9-like; Twinfilin-1-like protein |
| Protein Family: | Twinfilin |
| UniProt Gene Name: | TWF2 |
| UniProt Entry Name: | TWF2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TWF2 antibody (CAB13642) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
 | Immunoprecipitation analysis of 200ug extracts of 293T cells using 1ug TWF2 antibody (CAB13642). Western blot was performed from the immunoprecipitate using TWF2 antibody (CAB13642) at a dilition of 1:1000. |
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