UniProt Protein Function: | TSPYL5: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7. Belongs to the nucleosome assembly protein (NAP) family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 8q22.1 Molecular Function:protein binding Biological Process: positive regulation of cell proliferation; positive regulation of protein kinase B signaling cascade; positive regulation of protein ubiquitination |
UniProt Code: | Q86VY4 |
NCBI GenInfo Identifier: | 160198165 |
NCBI Gene ID: | 85453 |
NCBI Accession: | Q86VY4.2 |
UniProt Secondary Accession: | Q86VY4,Q9C0B3, B3KRF0, |
UniProt Related Accession: | Q86VY4 |
Molecular Weight: | 45,143 Da |
NCBI Full Name: | Testis-specific Y-encoded-like protein 5 |
NCBI Synonym Full Names: | TSPY like 5 |
NCBI Official Symbol: | TSPYL5 |
NCBI Protein Information: | testis-specific Y-encoded-like protein 5 |
UniProt Protein Name: | Testis-specific Y-encoded-like protein 5 |
Protein Family: | Testis-specific Y-encoded-like protein |
UniProt Gene Name: | TSPYL5 |
UniProt Entry Name: | TSYL5_HUMAN |