Anti-TSPAN6 Antibody (CAB17540)
- SKU:
- CAB17540
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-TSPAN6 Antibody |
| 抗体コード: | CAB17540 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-200 of human TSPAN6 (NP_003261.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-200 of human TSPAN6 (NP_003261.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | NSFK NNYE KALK QYNS TGDY RSHA VDKI QNTL HCCG VTDY RDWT DTNY YSEK GFPK SCCK LEDC TPQR DADK VNNE GCFI K |
| 遺伝子ID: | 7105 |
| Uniprot: | O43657 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 28kDa |
 | Western blot - TSPAN6 Polyclonal Antibody (CAB17540) |
| 同義語: | T245, TM4SF6, TSPAN-6, TSPAN6 |
| バックグラウンド: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013] |
| UniProt Protein Function: | TSPAN6: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: Xq22 Cellular Component: integral to plasma membrane Molecular Function:protein binding; signal transducer activity Biological Process: cell surface receptor linked signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade |
| NCBI Summary: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013] |
| UniProt Code: | O43657 |
| NCBI GenInfo Identifier: | 11135101 |
| NCBI Gene ID: | 7105 |
| NCBI Accession: | O43657.1 |
| UniProt Secondary Accession: | O43657,Q54A42, Q6IAN9, |
| UniProt Related Accession: | O43657 |
| Molecular Weight: | 27,563 Da |
| NCBI Full Name: | Tetraspanin-6 |
| NCBI Synonym Full Names: | tetraspanin 6 |
| NCBI Official Symbol: | TSPAN6 |
| NCBI Official Synonym Symbols: | T245; TM4SF6; TSPAN-6 |
| NCBI Protein Information: | tetraspanin-6 |
| UniProt Protein Name: | Tetraspanin-6 |
| UniProt Synonym Protein Names: | A15 homolog; Putative NF-kappa-B-activating protein 321; T245 protein; Tetraspanin TM4-D; Transmembrane 4 superfamily member 6 |
| UniProt Gene Name: | TSPAN6 |
| UniProt Entry Name: | TSN6_HUMAN |