Anti-TRIM41 Antibody (CAB3538)
- SKU:
- CAB3538
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-TRIM41 Antibody |
| 抗体コード: | CAB3538 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 421-630 of human TRIM41 (NP_291027.3). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, HeLa, LO2, Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 421-630 of human TRIM41 (NP_291027.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSRM FCQA ARVD LTLD PDTA HPAL MLSP DRRG VRLA ERRQ EVAD HPKR FSAD CCVL GAQG FRSG RHYW EVEV GGRR GWAV GAAR ESTH HKEK VGPG GSSV GSGD ASSS RHHH RRRR LHLP QQPL LQRE VWCV GTNG KRYQ AQSS TEQT LLSP SEKP RRFG VYLD YEAG RLGF YNAE TLAH VHTF SAAF LGER VFPF FRVL SKGT RIKL CP |
| 遺伝子ID: | 90933 |
| Uniprot: | Q8WV44 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 23kDa/43kDa/59kDa/71kDa |
| 観察された分子量: | 72kDa |
| 同義語: | TRIM41, RINCK |
| バックグラウンド: | This gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature motif composed of a RING finger, one or more B-box domains, and a coiled-coil region. This encoded protein may play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | TRIM41: Functions as an E3 ligase that catalyzes the ubiquitin- mediated degradation of protein kinase C. Belongs to the TRIM/RBCC family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system; Ubiquitin ligase; Ligase; EC 6.3.2.- Chromosomal Location of Human Ortholog: 5q35.3 Cellular Component: nucleolus Molecular Function:protein binding |
| NCBI Summary: | This gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature motif composed of a RING finger, one or more B-box domains, and a coiled-coil region. This encoded protein may play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q8WV44 |
| NCBI GenInfo Identifier: | 116242826 |
| NCBI Gene ID: | 90933 |
| NCBI Accession: | Q8WV44.3 |
| UniProt Secondary Accession: | Q8WV44,Q5BKT0, Q7L484, Q96Q10, Q9BSL8, B3KNJ6, D3DWR9 |
| UniProt Related Accession: | Q8WV44 |
| Molecular Weight: | 43,491 Da |
| NCBI Full Name: | E3 ubiquitin-protein ligase TRIM41 |
| NCBI Synonym Full Names: | tripartite motif containing 41 |
| NCBI Official Symbol: | TRIM41 |
| NCBI Official Synonym Symbols: | RINCK |
| NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM41 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM41 |
| UniProt Synonym Protein Names: | RING finger-interacting protein with C kinase; RINCK; Tripartite motif-containing protein 41 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | TRIM41 |
| UniProt Entry Name: | TRI41_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TRIM41 antibody (CAB3538) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 30s. |
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