Anti-TRIM16 Antibody (CAB17619)
- SKU:
- CAB17619
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-TRIM16 Antibody |
| 抗体コード: | CAB17619 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human TRIM16 (NP_006461.3). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse lung, Mouse thymus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human TRIM16 (NP_006461.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAEL DLMA PGPL PRAT AQPP APLS PDSG SPSP DSGS ASPV EEED VGSS EKLG RETE EQDS DSAE QGDP AGEG KEVL CDFC LDDT RRVK AVKS CLTC MVNY CEEH LQPH QVNI KLQS HLLT EPVK DHNW RYCP AHHS PLSA FCCP DQQC ICQD CCQE HSGH TIVS LDAA RRDK EAEL QCTQ LDLE RKLK LNEN AISR LQAN QKSV LVSV SE |
| 遺伝子ID: | 10626 |
| Uniprot: | O95361 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 64kDa |
 | Western blot - TRIM16 Polyclonal Antibody (CAB17619) |
| 同義語: | EBBP, TRIM16 |
| バックグラウンド: | The protein encoded by this gene is a tripartite motif (TRIM) family member that contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. While it lacks a RING domain found in other TRIM proteins, the encoded protein can homodimerize or heterodimerize with other TRIM proteins and has E3 ubiquitin ligase activity. This gene is also a tumor suppressor and is involved in secretory autophagy. [provided by RefSeq, Jan 2017] |
| UniProt Protein Function: | TRIM16: May play a role in the regulation of keratinocyte differentiation. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 17p11.2 Cellular Component: cytoplasm; PML body Molecular Function:DNA binding; interleukin-1 binding; NACHT domain binding; protein binding Biological Process: positive regulation of interleukin-1 beta secretion; positive regulation of keratinocyte differentiation; positive regulation of retinoic acid receptor signaling pathway; positive regulation of transcription, DNA-dependent; response to organophosphorus; response to retinoic acid |
| NCBI Summary: | This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95361 |
| NCBI GenInfo Identifier: | 145559535 |
| NCBI Gene ID: | 10626 |
| NCBI Accession: | O95361.3 |
| UniProt Secondary Accession: | O95361,Q6IAL8, Q7Z6I2, Q96BE8, Q96J43, |
| UniProt Related Accession: | O95361 |
| Molecular Weight: | 40,370 Da |
| NCBI Full Name: | Tripartite motif-containing protein 16 |
| NCBI Synonym Full Names: | tripartite motif containing 16 |
| NCBI Official Symbol: | TRIM16 |
| NCBI Official Synonym Symbols: | EBBP |
| NCBI Protein Information: | tripartite motif-containing protein 16 |
| UniProt Protein Name: | Tripartite motif-containing protein 16 |
| UniProt Synonym Protein Names: | Estrogen-responsive B box protein |
| Protein Family: | Tripartite motif-containing protein |
| UniProt Gene Name: | TRIM16 |
| UniProt Entry Name: | TRI16_HUMAN |