Anti-TRAPPC6A Antibody (CAB16143)
- SKU:
- CAB16143
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TRAPPC6A Antibody |
| 抗体コード: | CAB16143 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human TRAPPC6A (NP_077013.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse kidney, Rat kidney, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human TRAPPC6A (NP_077013.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MADT VLFE FLHT EMVA ELWA HDPD PGPG VSAG LRGE EAGA TKGQ KMSL SVLE GMGF RVGQ ALGE RLPR ETLA FREE LDVL KFLC KDLW VAVF QKQM DSLR TNHQ GTYV LQDN SFPL LLPM ASGL QYLE EAPK FLAF TCGL LRGA LYTL GIES VVTA SVAA LPVC KFQV VIPK S |
| 遺伝子ID: | 79090 |
| Uniprot: | O75865 |
| セルラーロケーション: | Endoplasmic reticulum, Golgi apparatus, cis-Golgi network |
| 計算された分子量: | 11kDa/12kDa/17kDa/18kDa |
| 観察された分子量: | 18kDa |
| 同義語: | TRAPPC6A, TRS33 |
| バックグラウンド: | This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. Loss of expression of the related gene in mouse affects coat and eye pigmentation, suggesting that the encoded protein may be involved in melanosome biogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| UniProt Protein Function: | TRAPPC6A: May play a role in vesicular transport during the biogenesis of melanosomes. Belongs to the TRAPP small subunits family. BET3 subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19q13.32 Cellular Component: cytosol Molecular Function:protein binding Biological Process: COPII coating of Golgi vesicle |
| NCBI Summary: | This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. Loss of expression of the related gene in mouse affects coat and eye pigmentation, suggesting that the encoded protein may be involved in melanosome biogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012] |
| UniProt Code: | O75865 |
| NCBI GenInfo Identifier: | 109895221 |
| NCBI Gene ID: | 79090 |
| NCBI Accession: | O75865.2 |
| UniProt Secondary Accession: | O75865,Q9BQ45, Q9P092, K7ERB1, K7ERQ4, |
| UniProt Related Accession: | O75865 |
| Molecular Weight: | 12,976 Da |
| NCBI Full Name: | Trafficking protein particle complex subunit 6A |
| NCBI Synonym Full Names: | trafficking protein particle complex 6A |
| NCBI Official Symbol: | TRAPPC6A |
| NCBI Official Synonym Symbols: | TRS33 |
| NCBI Protein Information: | trafficking protein particle complex subunit 6A |
| UniProt Protein Name: | Trafficking protein particle complex subunit 6A |
| Protein Family: | Trafficking protein particle complex |
| UniProt Gene Name: | TRAPPC6A |
| UniProt Entry Name: | TPC6A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TRAPPC6A antibody (CAB16143) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunofluorescence analysis of L929 cells using TRAPPC6A antibody (CAB16143) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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