Anti-TRAPPC2 Antibody (CAB10465)
- SKU:
- CAB10465
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TRAPPC2 Antibody |
| 抗体コード: | CAB10465 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TRAPPC2 (NP_055378.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | LO2, 293T, SW620 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TRAPPC2 (NP_055378.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSGS FYFV IVGH HDNP VFEM EFLP AGKA ESKD DHRH LNQF IAHA ALDL VDEN MWLS NNMY LKTV DKFN EWFV SAFV TAGH MRFI MLHD IRQE DGIK NFFT DVYD LYIK FSMN PFYE PNSP IRSS AFDR KVQF LGKK HLLS |
| 遺伝子ID: | 6399 |
| Uniprot: | P0DI81 |
| セルラーロケーション: | Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Nucleus, perinuclear region |
| 計算された分子量: | 14kDa/16kDa/20kDa |
| 観察された分子量: | 16kDa |
| 同義語: | TRAPPC2, MIP2A, SEDL, SEDT, TRAPPC2P1, TRS20, ZNF547L, hYP38334 |
| バックグラウンド: | The protein encoded by this gene is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | TRAPPC2: Prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. May play a role in vesicular transport from endoplasmic reticulum to Golgi. Belongs to the TRAPP small subunits family. Sedlin subfamily. Part of the multisubunit TRAPP (transport protein particle) complex. Interacts with MBP1 and TRAPPC2L. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: Xp22 Cellular Component: Golgi apparatus; perinuclear region of cytoplasm; endoplasmic reticulum; nucleus Molecular Function:protein binding; transcription factor binding Biological Process: ER to Golgi vesicle-mediated transport; regulation of transcription, DNA-dependent; transcription, DNA-dependent; skeletal development Disease: Spondyloepiphyseal Dysplasia Tarda, X-linked |
| NCBI Summary: | The protein encoded by this gene is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010] |
| UniProt Code: | P0DI81 |
| NCBI GenInfo Identifier: | 347662477 |
| NCBI Gene ID: | 6399 |
| NCBI Accession: | P0DI81.1 |
| UniProt Related Accession: | P0DI81 |
| Molecular Weight: | 16kDa |
| NCBI Full Name: | Trafficking protein particle complex subunit 2 |
| NCBI Synonym Full Names: | trafficking protein particle complex 2 |
| NCBI Official Symbol: | TRAPPC2 |
| NCBI Official Synonym Symbols: | SEDL; SEDT; MIP2A; TRS20; ZNF547L; hYP38334; TRAPPC2P1 |
| NCBI Protein Information: | trafficking protein particle complex subunit 2 |
| UniProt Protein Name: | Trafficking protein particle complex subunit 2 |
| UniProt Synonym Protein Names: | Sedlin |
| Protein Family: | Trafficking protein particle complex |
| UniProt Gene Name: | TRAPPC2 |
| UniProt Entry Name: | TPC2A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TRAPPC2 antibody (CAB10465) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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