Anti-TRAF3IP1 Antibody (CAB8997)
- SKU:
- CAB8997
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TRAF3IP1 Antibody |
| 抗体コード: | CAB8997 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 386-625 of human TRAF3IP1 (NP_001132962.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:1000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, 293T, A-549, Mouse kidney, Mouse testis, Mouse brain, Mouse lung, Rat kidney, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 386-625 of human TRAF3IP1 (NP_001132962.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SSNI RRIP RPGS ARPA PPRV KRQD SMEA LQMD RSGS GKTV SNVI TESH NSDN EEDD QFVV EAAP QLSE MSEI EMVT AVEL EEEE KHGG LVKK ILET KKDY EKLQ QSPK PGEK ERSL FESA WKKE KDIV SKEI EKLR TSIQ TLCK SALP LGKI MDYI QEDV DAMQ NELQ MWHS ENRQ HAEA LQQE QRIT DCAV EPLK AELA ELEQ LIKD QQDK ICAV KANI LKNE EKIQ KMVY SINL TSRR |
| 遺伝子ID: | 26146 |
| Uniprot: | Q8TDR0 |
| セルラーロケーション: | Cell projection, Cytoplasm, cilium, cytoskeleton |
| 計算された分子量: | 71kDa/78kDa |
| 観察された分子量: | 79kDa |
| 同義語: | TRAF3IP1, IFT54, MIP-T3, MIPT3, SLSN9 |
| バックグラウンド: | The protein encoded by this gene interacts with TNF receptor-associated factor 3, tethering it to cytoskeletal microtubules. The encoded protein is also an inhibitor of the innate type I IFN response. Defects in this gene are a cause of Senior-Loken syndrome 9. |
| UniProt Protein Function: | TRAF3IP1: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Belongs to the TRAF3IP1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Microtubule-binding Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: centrosome Molecular Function:protein binding Biological Process: cilium biogenesis; intraflagellar transport; kidney development; morphogenesis of a polarized epithelium; negative regulation of defense response to virus; negative regulation of interferon type I production; negative regulation of protein amino acid phosphorylation; negative regulation of protein complex assembly |
| UniProt Code: | Q8TDR0 |
| NCBI GenInfo Identifier: | 74727348 |
| NCBI Gene ID: | 26146 |
| NCBI Accession: | Q8TDR0.1 |
| UniProt Secondary Accession: | Q8TDR0,Q6PCT1, Q7L8N9, Q9NRD6, Q9Y4Q1, |
| UniProt Related Accession: | Q8TDR0 |
| Molecular Weight: | 71,529 Da |
| NCBI Full Name: | TRAF3-interacting protein 1 |
| NCBI Synonym Full Names: | TRAF3 interacting protein 1 |
| NCBI Official Symbol: | TRAF3IP1 |
| NCBI Official Synonym Symbols: | IFT54; MIPT3; SLSN9; MIP-T3 |
| NCBI Protein Information: | TRAF3-interacting protein 1 |
| UniProt Protein Name: | TRAF3-interacting protein 1 |
| UniProt Synonym Protein Names: | Interleukin-13 receptor alpha 1-binding protein 1; Intraflagellar transport protein 54 homolog; Microtubule-interacting protein associated with TRAF3; MIP-T3 |
| Protein Family: | TRAF3-interacting protein |
| UniProt Gene Name: | TRAF3IP1 |
| UniProt Entry Name: | MIPT3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TRAF3IP1 antibody (CAB8997) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s. |
View AllClose