Anti-TRABD2B Antibody (CAB18570)
- SKU:
- CAB18570
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-TRABD2B Antibody |
| 抗体コード: | CAB18570 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human TRABD2B. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant protein of human TRABD2B. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 666048 |
| Uniprot: | A6NFA1 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | Refer to figures |
| 同義語: | Gm12824, Hkat, TRABD2B |
| バックグラウンド: |
| UniProt Protein Function: | LOC388630: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N- terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. Belongs to the TIKI family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 1p33 Cellular Component: integral to plasma membrane Molecular Function:Wnt-protein binding; protein binding; metal ion binding; metalloendopeptidase activity Biological Process: Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; protein amino acid oxidation; metabolic process; proteolysis |
| UniProt Code: | A6NFA1 |
| NCBI GenInfo Identifier: | 303228327 |
| NCBI Gene ID: | 388630 |
| NCBI Accession: | NP_001181915.1 |
| UniProt Secondary Accession: | A6NFA1,I6U4Y0, |
| UniProt Related Accession: | A6NFA1 |
| Molecular Weight: | 57,421 Da |
| NCBI Full Name: | metalloprotease TIKI2 |
| NCBI Synonym Full Names: | TraB domain containing 2B |
| NCBI Official Symbol: | TRABD2B |
| NCBI Official Synonym Symbols: | TIKI2 |
| NCBI Protein Information: | metalloprotease TIKI2 |
| UniProt Protein Name: | Metalloprotease TIKI2 |
| UniProt Synonym Protein Names: | Heart, kidney and adipose-enriched transmembrane protein homolog; TRAB domain-containing protein 2B |
| Protein Family: | Metalloprotease |
| UniProt Gene Name: | TRABD2B |
| UniProt Entry Name: | TIKI2_HUMAN |