Anti-TPP2 Antibody (CAB6421)
- SKU:
- CAB6421
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-TPP2 Antibody |
抗体コード: | CAB6421 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TPP2 (NP_003282.2). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Jurkat, SW620, HeLa, HepG2, Mouse brain, Mouse spleen |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TPP2 (NP_003282.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MATA ATEE PFPF HGLL PKKE TGAA SFLC RYPE YDGR GVLI AVLD TGVD PGAP GMQV TTDG KPKI VDII DTTG SGDV NTAT EVEP KDGE IVGL SGRV LKIP ASWT NPSG KYHI GIKN GYDF YPKA LKER IQKE RKEK IWDP VHRV ALAE ACRK QEEF DVAN NGSS QANK LIKE ELQS QVEL LNSF EKKY SDPG PVYD CLVW HDGE VWRA CIDS NEDG DLSK STVL RNYK EAQE YGSF GTAE MLNY SVNI YDDG NLLS IVTS GGAH GTHV ASIA AGHF PEEP ERNG VAPG AQIL SIKI GDTR |
遺伝子ID: | 7174 |
Uniprot: | P29144 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 138kDa |
観察された分子量: | 138kDa |
同義語: | TPP2, TPP-2, TPP-II, TPPII |
バックグラウンド: | This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class. |
UniProt Protein Function: | TPP2: Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Belongs to the peptidase S8 family. |
UniProt Protein Details: | Protein type:EC 3.4.14.10; Protease Chromosomal Location of Human Ortholog: 13q32-q33 Cellular Component: nucleoplasm; cytoplasm; cytosol; nucleus Molecular Function:tripeptidyl-peptidase activity; serine-type endopeptidase activity; endopeptidase activity; aminopeptidase activity Biological Process: antigen processing and presentation of peptide antigen via MHC class I; protein polyubiquitination; proteolysis |
NCBI Summary: | This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class. [provided by RefSeq, Jul 2008] |
UniProt Code: | P29144 |
NCBI GenInfo Identifier: | 34223721 |
NCBI Gene ID: | 7174 |
NCBI Accession: | P29144.4 |
UniProt Secondary Accession: | P29144,Q5VZU8, |
UniProt Related Accession: | P29144 |
Molecular Weight: | 1249 |
NCBI Full Name: | Tripeptidyl-peptidase 2 |
NCBI Synonym Full Names: | tripeptidyl peptidase II |
NCBI Official Symbol: | TPP2 |
NCBI Official Synonym Symbols: | TPP-2 |
NCBI Protein Information: | tripeptidyl-peptidase 2; TPP-II; tripeptidyl-peptidase II; tripeptidyl aminopeptidase |
UniProt Protein Name: | Tripeptidyl-peptidase 2 |
UniProt Synonym Protein Names: | Tripeptidyl aminopeptidase; Tripeptidyl-peptidase II; TPP-II |
Protein Family: | Tripeptidyl-peptidase |
UniProt Gene Name: | TPP2 |
UniProt Entry Name: | TPP2_HUMAN |
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