Anti-TPD52L1 Antibody (CAB6420)
- SKU:
- CAB6420
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TPD52L1 Antibody |
| 抗体コード: | CAB6420 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human TPD52L1 (NP_001003396.1). |
| 申し込み: | IF |
| 推奨希釈: | IF 1:20 - 1:50 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human TPD52L1 (NP_001003396.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MEAQ AQGL LETE PLQG TDED AVAS ADFS SMLS EEEK EELK AELV QLED EITT LRQV LSAK ERHL VEIK QKLG MNLM NELK QNFS KSWH DMQT TTAY KKTH ETLS HAGQ KATA AFSN VGTA ISKK FGDM SYSI RHSI SMPA MRRK |
| 遺伝子ID: | 7164 |
| Uniprot: | Q16890 |
| セルラーロケーション: | |
| 計算された分子量: | 11kDa/14kDa/16kDa/19kDa/22kDa |
| 観察された分子量: |
| 同義語: | TPD52L1, D53 |
| バックグラウンド: | This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. |
| UniProt Protein Function: | TPD52L1: a member of the tumor protein D52 (TPD52) family. Contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. Interacts with the apoptosis signal-regulating kinase 1 (ASK1) and positively regulates ASK1-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 6q22-q23 Cellular Component: perinuclear region of cytoplasm; cytoplasm Molecular Function:identical protein binding; protein binding; protein homodimerization activity; protein heterodimerization activity Biological Process: positive regulation of MAP kinase activity; positive regulation of JNK cascade; G2/M transition of mitotic cell cycle; regulation of caspase activity |
| NCBI Summary: | This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. [provided by RefSeq, Jan 2016] |
| UniProt Code: | Q16890 |
| NCBI GenInfo Identifier: | 12585368 |
| NCBI Gene ID: | 7164 |
| NCBI Accession: | Q16890.1 |
| UniProt Related Accession: | Q16890 |
| Molecular Weight: | |
| NCBI Full Name: | Tumor protein D53 |
| NCBI Synonym Full Names: | TPD52 like 1 |
| NCBI Official Symbol: | TPD52L1 |
| NCBI Official Synonym Symbols: | D53 |
| NCBI Protein Information: | tumor protein D53 |
| UniProt Protein Name: | Tumor protein D53 |
| UniProt Synonym Protein Names: | Tumor protein D52-like 1 |
| UniProt Gene Name: | TPD52L1 |
| UniProt Entry Name: | TPD53_HUMAN |
 | Immunofluorescence analysis of U2OS cells using TPD52L1 antibody (CAB6420). Blue: DAPI for nuclear staining. |
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