Anti-TOMM22 Antibody (RACO0581)
- SKU:
- RACO0581
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- WB
- Application:
- ELISA
- Application:
- IHC
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 商品名: | TOMM22 Antibody |
| Product SKU: | RACO0581 |
| サイズ: | 50ul |
| 宿主種: | Homo sapiens (Human) |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | WB:1:500-1:5000, IHC:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | A synthesized peptide derived from human TOMM22 |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | Affinity-chromatography |
| 抗体のクローン性: | Monoclonal |
| アイソタイプ: | Rabbit IgG |
| Conjugate: | Non-conjugated |
| バックグラウンド: | Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore. |
| シノニム: | Mitochondrial import receptor subunit TOM22 homolog (hTom22) (1C9-2) (Translocase of outer membrane 22 kDa subunit homolog), TOMM22, TOM22 |
 | IHC image of RACO0581 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
 | Western Blot. Positive WB detected in 293 whole cell lysate Hela whole cell lysate L02 whole cell lysate HepF2 whole cell lysate Raji whole cell lysate Jurkat whole cell lysate K562 whole cell lysate All lanes TOMM22 antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1:50000 dilution. Predicted band size: 16 kDa. Observed band size: 18 kDa. |
| UniProt Protein Function: | TOMM22: Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore. Belongs to the Tom22 family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Membrane protein, integral Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: mitochondrion; membrane; mitochondrial outer membrane translocase complex; mitochondrial inner membrane; integral to membrane Molecular Function:protein binding; protein transmembrane transporter activity Biological Process: cellular protein metabolic process; protein targeting to mitochondrion; protein import into mitochondrial outer membrane |
| NCBI Summary: | The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NS69 |
| NCBI GenInfo Identifier: | 24212074 |
| NCBI Gene ID: | 56993 |
| NCBI Accession: | Q9NS69.3 |
| UniProt Secondary Accession: | Q9NS69,Q9CPQ3, |
| UniProt Related Accession: | Q9NS69 |
| Molecular Weight: | 142 |
| NCBI Full Name: | Mitochondrial import receptor subunit TOM22 homolog |
| NCBI Synonym Full Names: | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| NCBI Official Symbol: | TOMM22 |
| NCBI Official Synonym Symbols: | 1C9-2; TOM22; MST065; MSTP065 |
| NCBI Protein Information: | mitochondrial import receptor subunit TOM22 homolog; mitochondrial import receptor Tom22; translocase of outer membrane 22 kDa subunit homolog |
| UniProt Protein Name: | Mitochondrial import receptor subunit TOM22 homolog |
| UniProt Synonym Protein Names: | 1C9-2; Translocase of outer membrane 22 kDa subunit homolog |
| Protein Family: | Mitochondrial import receptor |
| UniProt Gene Name: | TOMM22 |
| UniProt Entry Name: | TOM22_HUMAN |