Anti-TNFRSF17 Antibody (CAB10707)
- SKU:
- CAB10707
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- TNFRSF17
- Synonyms:
- BCM
- Synonyms:
- BCMA
- Synonyms:
- CD269
- Synonyms:
- TNFRSF13A
Frequently bought together:
Description
| I抗体名: | TNFRSF17 Rabbit pAb |
| 抗体コード: | CAB10707 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | TNFRSF17, BCM, BCMA, CD269, TNFRSF13A |
| 申し込み: | WB, IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNFRSF17 (NP_001183.2). |
| 申し込み: | WB, IF |
| 推奨される希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | SP2/0, Raji, Rat spleen |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNFRSF17 (NP_001183.2). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MLQM AGQC SQNE YFDS LLHA CIPC QLRC SSNT PPLT CQRY CNAS VTNS VKGT NAIL WTCL GLSL IISL AVFV LMFL LRKI NSEP LKDE FKNT GSGL LGMA |
| 遺伝子ID: | 608 |
| Uniprot: | Q02223 |
| セルラーロケーション: | Cell membrane, Endomembrane system, Single-pass type III membrane protein |
| 計算された分子量: | 14kDa/20kDa |
| 観察された分子量: | 15-35kDa |
| UniProt Protein Function: | TNFRSF17: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.Protein type: Oncoprotein; Receptor, misc.; Membrane protein, integralChromosomal Location of Human Ortholog: 16p13.1Cellular Component: endomembrane system; integral to membrane; plasma membraneMolecular Function: receptor activityBiological Process: adaptive immune response; cell proliferation; lymphocyte homeostasis; multicellular organismal development; signal transduction; tumor necrosis factor-mediated signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q02223 |
| NCBI GenInfo Identifier: | 313104029 |
| NCBI Gene ID: | 608 |
| NCBI Accession: | Q02223.2 |
| UniProt Secondary Accession: | Q02223,Q2TQ40 |
| UniProt Related Accession: | Q02223 |
| Molecular Weight: | 14,843 Da |
| NCBI Full Name: | Tumor necrosis factor receptor superfamily member 17 |
| NCBI Synonym Full Names: | tumor necrosis factor receptor superfamily member 17 |
| NCBI Official Symbol: | TNFRSF17 |
| NCBI Official Synonym Symbols: | BCM; BCMA; CD269; TNFRSF13A |
| NCBI Protein Information: | tumor necrosis factor receptor superfamily member 17 |
| UniProt Protein Name: | Tumor necrosis factor receptor superfamily member 17 |
| UniProt Synonym Protein Names: | B-cell maturation protein; CD_antigen: CD269 |
| Protein Family: | |
| UniProt Gene Name: | TNFRSF17 |
| UniProt Entry Name: | TNR17_HUMAN |
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