Anti-TNFAIP6 Antibody (CAB6419)
- SKU:
- CAB6419
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TNFAIP6 Antibody |
| 抗体コード: | CAB6419 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-277 of human TNFAIP6 (NP_009046.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-277 of human TNFAIP6 (NP_009046.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | WGFK DGIF HNSI WLER AAGV YHRE ARSG KYKL TYAE AKAV CEFE GGHL ATYK QLEA ARKI GFHV CAAG WMAK GRVG YPIV KPGP NCGF GKTG IIDY GIRL NRSE RWDA YCYN PHAK ECGG VFTD PKQI FKSP GFPN EYED NQIC YWHI RLKY GQRI HLSF LDFD LEDD PGCL ADYV EIYD SYDD VHGF VGRY CGDE LPDD IIST GNVM TLKF LSDA SVTA GGFQ IKYV AMDP VSKS SQGK NTST TSTG NKNF LAGR FSHL |
| 遺伝子ID: | 7130 |
| Uniprot: | P98066 |
| セルラーロケーション: | |
| 計算された分子量: | 31kDa |
| 観察された分子量: | 40kDa |
| 同義語: | TNFAIP6, TSG-6, TSG6 |
| バックグラウンド: | The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis. |
| UniProt Protein Function: | TNFAIP6: Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2q23.3 Cellular Component: extracellular space Molecular Function:hyaluronic acid binding Biological Process: ovulation; cell-cell signaling; signal transduction; inflammatory response; cell adhesion; positive regulation of cell migration |
| NCBI Summary: | The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010] |
| UniProt Code: | P98066 |
| NCBI GenInfo Identifier: | 68067717 |
| NCBI Gene ID: | 7130 |
| NCBI Accession: | P98066.2 |
| UniProt Secondary Accession: | P98066,Q53TI7, Q8WWI9, |
| UniProt Related Accession: | P98066 |
| Molecular Weight: | 277 |
| NCBI Full Name: | Tumor necrosis factor-inducible gene 6 protein |
| NCBI Synonym Full Names: | tumor necrosis factor, alpha-induced protein 6 |
| NCBI Official Symbol: | TNFAIP6 |
| NCBI Official Synonym Symbols: | TSG6; TSG-6 |
| NCBI Protein Information: | tumor necrosis factor-inducible gene 6 protein; TNF alpha-induced protein 6; hyaluronate-binding protein; TNF-stimulated gene 6 protein; tumor necrosis factor alpha-inducible protein 6; tumor necrosis factor-stimulated gene-6 protein |
| UniProt Protein Name: | Tumor necrosis factor-inducible gene 6 protein |
| UniProt Synonym Protein Names: | Hyaluronate-binding protein; TNF-stimulated gene 6 protein; TSG-6; Tumor necrosis factor alpha-induced protein 6; TNF alpha-induced protein 6 |
| Protein Family: | Tumor necrosis factor-inducible gene 6 protein |
| UniProt Gene Name: | TNFAIP6 |
| UniProt Entry Name: | TSG6_HUMAN |
 | Western blot analysis of extracts of mouse brain, using TNFAIP6 Antibody (CAB6419) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human stomach using TNFAIP6 antibody (CAB6419) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat kidney using TNFAIP6 antibody (CAB6419) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse heart using TNFAIP6 antibody (CAB6419) at dilution of 1:100 (40x lens). |
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