Anti-TMOD2 Antibody (CAB14881)
- SKU:
- CAB14881
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TMOD2 Antibody |
| 抗体コード: | CAB14881 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-200 of human TMOD2 (NP_055363.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Mouse testis, Rat brain, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-200 of human TMOD2 (NP_055363.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | EEAL ASAS DTEL YDLA AVLG VHNL LNNP KFDE ETAN NKGG KGPV RNVV KGEK VKPV FEEP PNPT NVEI SLQQ MKAN DPSL Q |
| 遺伝子ID: | 29767 |
| Uniprot: | Q9NZR1 |
| セルラーロケーション: | Cytoplasm, cytoskeleton |
| 計算された分子量: | 35kDa/39kDa |
| 観察された分子量: | 40kDa |
| 同義語: | TMOD2, N-TMOD, NTMOD |
| バックグラウンド: | This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. |
| UniProt Protein Function: | TMOD2: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. Belongs to the tropomodulin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 15q21.2 Cellular Component: striated muscle thin filament Biological Process: actin filament organization; muscle contraction; myofibril assembly; nervous system development |
| NCBI Summary: | This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2008] |
| UniProt Code: | Q9NZR1 |
| NCBI GenInfo Identifier: | 23396886 |
| NCBI Gene ID: | 29767 |
| NCBI Accession: | Q9NZR1.1 |
| UniProt Secondary Accession: | Q9NZR1,B4DEW6, |
| UniProt Related Accession: | Q9NZR1 |
| Molecular Weight: | 35,648 Da |
| NCBI Full Name: | Tropomodulin-2 |
| NCBI Synonym Full Names: | tropomodulin 2 |
| NCBI Official Symbol: | TMOD2 |
| NCBI Official Synonym Symbols: | NTMOD; N-TMOD |
| NCBI Protein Information: | tropomodulin-2 |
| UniProt Protein Name: | Tropomodulin-2 |
| UniProt Synonym Protein Names: | Neuronal tropomodulin; N-Tmod |
| Protein Family: | Tropomodulin |
| UniProt Gene Name: | TMOD2 |
| UniProt Entry Name: | TMOD2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TMOD2 antibody (CAB14881) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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