Anti-TKTL1 Antibody (CAB15337)
- SKU:
- CAB15337
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TKTL1 Antibody |
| 抗体コード: | CAB15337 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human TKTL1 (NP_036385.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | LO2, 293T, A-549, BxPC-3, Mouse testis, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human TKTL1 (NP_036385.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RGTP SIED AESW HAKP MPRE RADA IIKL IESQ IQTS RNLD PQPP IEDS PEVN ITDV RMTS PPDY RVGD KIAT RKAC GLAL AKLG YANN RVVV LDGD TRYS TFSE IFNK EYPE RFIE CFMA E |
| 遺伝子ID: | 8277 |
| Uniprot: | P51854 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 59kDa/61kDa/65kDa |
| 観察された分子量: | 65kDa |
| 同義語: | TKTL1, TKR, TKT2 |
| バックグラウンド: | The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. |
| NCBI Summary: | The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
| UniProt Code: | P51854 |
| NCBI GenInfo Identifier: | 122066426 |
| NCBI Gene ID: | 8277 |
| NCBI Accession: | P51854.2 |
| UniProt Secondary Accession: | P51854,Q5TYJ8, Q5TYJ9, Q8TC75, A8K896, |
| UniProt Related Accession: | P51854 |
| Molecular Weight: | – Da |
| NCBI Full Name: | Transketolase-like protein 1 |
| NCBI Synonym Full Names: | transketolase like 1 |
| NCBI Official Symbol: | TKTL1 |
| NCBI Official Synonym Symbols: | TKR; TKT2 |
| NCBI Protein Information: | transketolase-like protein 1 |
| UniProt Protein Name: | Transketolase-like protein 1 |
| UniProt Synonym Protein Names: | Transketolase 2; TK 2; Transketolase-related protein |
| Protein Family: | Transketolase-like protein |
| UniProt Gene Name: | TKTL1 |
 | Western blot analysis of extracts of various cell lines, using TKTL1 antibody (CAB15337) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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