Anti-TKT Antibody (CAB6314)
- SKU:
- CAB6314
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TKT Antibody |
| 抗体コード: | CAB6314 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TKT (NP_001128527.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, 293T, Jurkat, MCF7, U-251MG, HepG2, Mouse liver, Mouse kidney, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TKT (NP_001128527.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MESY HKPD QQKL QALK DTAN RLRI SSIQ ATTA AGSG HPTS CCSA AEIM AVLF FHTM RYKS QDPR NPHN DRFV LSKG HAAP ILYA VWAE AGFL AEAE LLNL RKIS SDLD GHPV PKQA FTDV ATGS LGQG LGAA CGMA YTGK YFDK ASYR VYCL LGDG ELSE GSVW EAMA FASI YKLD NLVA ILDI NRLG QSDP APLQ HQMD IYQK RCEA FGWH AIIV DGHS VEEL CKAF GQAK HQPT AIIA KTFK GRGI TGVE DKES WHGK PLPK NMAE QIIQ EIYS QIQS |
| 遺伝子ID: | 7086 |
| Uniprot: | P29401 |
| セルラーロケーション: | |
| 計算された分子量: | 67kDa/68kDa |
| 観察された分子量: | 68kDa |
| 同義語: | TKT, HEL-S-48, HEL107, SDDHD, TK, TKT1 |
| バックグラウンド: | This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| UniProt Protein Function: | TKT: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. Homodimer. Belongs to the transketolase family. |
| UniProt Protein Details: | Protein type:Transferase; EC 2.2.1.1; Carbohydrate Metabolism - pentose phosphate pathway Chromosomal Location of Human Ortholog: 3p14.3 Cellular Component: nucleoplasm; peroxisome; nucleus; cytosol; vesicle Molecular Function:transketolase activity; protein homodimerization activity; metal ion binding; cofactor binding Biological Process: pentose-phosphate shunt; regulation of growth; carbohydrate metabolic process; energy reserve metabolic process; glyceraldehyde-3-phosphate biosynthetic process; pentose-phosphate shunt, non-oxidative branch; xylulose biosynthetic process; pathogenesis Disease: Wernicke-korsakoff Syndrome |
| NCBI Summary: | This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012] |
| UniProt Code: | P29401 |
| NCBI GenInfo Identifier: | 1729976 |
| NCBI Gene ID: | 7086 |
| NCBI Accession: | P29401.3 |
| UniProt Secondary Accession: | P29401,Q8TBA3, Q96HH3, A8K089, B4DE31, E7EPA7, |
| UniProt Related Accession: | P29401 |
| Molecular Weight: | 623 |
| NCBI Full Name: | Transketolase |
| NCBI Synonym Full Names: | transketolase |
| NCBI Official Symbol: | TKT |
| NCBI Official Synonym Symbols: | TK; TKT1; HEL107 |
| NCBI Protein Information: | transketolase; epididymis luminal protein 107 |
| UniProt Protein Name: | Transketolase |
| Protein Family: | Transketolase |
| UniProt Gene Name: | TKT |
| UniProt Entry Name: | TKT_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TKT antibody (CAB6314) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 60s. |
 | Immunohistochemistry of paraffin-embedded Rat liver using TKT Rabbit pAb (CAB6314) at dilution of 1:50 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Human esophageal using TKT Rabbit pAb (CAB6314) at dilution of 1:50 (40x lens). |
View AllClose