Anti-TKFC Antibody (CAB15421)
- SKU:
- CAB15421
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TKFC Antibody |
| 抗体コード: | CAB15421 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 226-575 of human TKFC (NP_056348.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, LO2, HeLa, Mouse heart, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 226-575 of human TKFC (NP_056348.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VRRI KMAT ADEI VKLM LDHM TNTT NASH VPVQ PGSS VVMM VNNL GGLS FLEL GIIA DATV RSLE GRGV KIAR ALVG TFMS ALEM PGIS LTLL LVDE PLLK LIDA ETTA AAWP NVAA VSIT GRKR SRVA PAEP QEAP DSTA AGGS ASKR MALV LERV CSTL LGLE EHLN ALDR AAGD GDCG TTHS RAAR AIQE WLKE GPPP ASPA QLLS KLSV LLLE KMGG SSGA LYGL FLTA AAQP LKAK TSLP AWSA AMDA GLEA MQKY GKAA PGDR TMLD SLWA AGQE LQAW KSPG ADLL QVLT KAVK SAEA AAEA TKNM EAGA GRAS YISS ARLE QPDP GAVA AAAI LRAI LEVL QS |
| 遺伝子ID: | 26007 |
| Uniprot: | Q3LXA3 |
| セルラーロケーション: | |
| 計算された分子量: | 54kDa/58kDa |
| 観察された分子量: | 60kDa |
| 同義語: | TKFC, DAK, NET45 |
| バックグラウンド: | This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4', 5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response (PubMed:17600090). |
| NCBI Summary: | This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4',5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2017] |
| UniProt Code: | Q3LXA3 |
| NCBI GenInfo Identifier: | 20149621 |
| NCBI Gene ID: | 26007 |
| NCBI Accession: | NP_056348.2 |
| UniProt Secondary Accession: | Q3LXA3,Q2L9C1, Q53EQ9, Q9BVA7, Q9H895, |
| UniProt Related Accession: | Q3LXA3 |
| Molecular Weight: | 54,793 Da |
| NCBI Full Name: | triokinase/FMN cyclase isoform b |
| NCBI Synonym Full Names: | triokinase and FMN cyclase |
| NCBI Official Symbol: | TKFC |
| NCBI Official Synonym Symbols: | DAK; NET45 |
| NCBI Protein Information: | triokinase/FMN cyclase |
| UniProt Protein Name: | Triokinase/FMN cyclase |
| UniProt Synonym Protein Names: | Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)Including the following 2 domains:ATP-dependent dihydroxyacetone kinase (EC:2.7.1.28, EC:2.7.1.29); DHA kinaseAlternative name(s):Glycerone kinase; Triokinase; Triose kinase |
| Protein Family: | Dihydroxyacetone kinase |
| UniProt Gene Name: | TKFC |
 | Western blot analysis of extracts of various cell lines, using TKFC antibody (CAB15421). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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