Anti-TIPIN Antibody (CAB10344)
- SKU:
- CAB10344
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-TIPIN Antibody |
| 抗体コード: | CAB10344 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human TIPIN (NP_060328.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | 293T, HeLa, MCF7 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human TIPIN (NP_060328.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MLEP QENG VIDL PDYE HVED ETFP PFPP PASP ERQD GEGT EPDE ESGN GAPV PVPP KRTV KRNI PKLD AQRL ISER GLPA LRHV FDKA KFKG KGHE AEDL KMLI RHME HWAH RLFP KLQF EDFI DRVE YLGS KKEV QTCL KRIR LDLP ILHE DFVS NNDE VAEN NEHD VTST ELDP FLTN LSES EMFA SELS RSLT EEQQ QRIE RNKQ LALE RRQA KLLS NSQT LGND MLMN TPRA HTVE EVNT DEDQ KEES NGLN EDIL DNPC NDAI ANTL NEEE TLLD QSFK NVQQ QLDA TSRN ITEA R |
| 遺伝子ID: | 54962 |
| Uniprot: | Q9BVW5 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 34kDa |
| 観察された分子量: | 50kDa |
| 同義語: | TIPIN |
| バックグラウンド: | The protein encoded by this gene is part of the replisome complex, a group of proteins that support DNA replication. It binds TIM, which is involved in circadian rhythm regulation, and aids in protecting cells against DNA damage and stress. Two pseudogenes and two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | TIPIN: Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Belongs to the CSM3 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 15q22.31 Cellular Component: intracellular membrane-bound organelle; nuclear chromatin; nucleoplasm; nucleus Molecular Function:DNA binding; protein binding Biological Process: DNA replication; DNA replication checkpoint; intra-S DNA damage checkpoint; positive regulation of cell proliferation; regulation of DNA replication during S phase; replication fork arrest; replication fork protection |
| NCBI Summary: | The protein encoded by this gene is part of the replisome complex, a group of proteins that support DNA replication. It binds TIM, which is involved in circadian rhythm regulation, and aids in protecting cells against DNA damage and stress. Two pseudogenes and two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q9BVW5 |
| NCBI GenInfo Identifier: | 296452932 |
| NCBI Gene ID: | 54962 |
| NCBI Accession: | Q9BVW5.2 |
| UniProt Secondary Accession: | Q9BVW5,Q9NWZ6, B2CW64, |
| UniProt Related Accession: | Q9BVW5 |
| Molecular Weight: | 35kDa |
| NCBI Full Name: | TIMELESS-interacting protein |
| NCBI Synonym Full Names: | TIMELESS interacting protein |
| NCBI Official Symbol: | TIPIN |
| NCBI Protein Information: | TIMELESS-interacting protein |
| UniProt Protein Name: | TIMELESS-interacting protein |
| Protein Family: | TIMELESS-interacting protein |
| UniProt Gene Name: | TIPIN |
 | Western blot analysis of extracts of various cell lines, using TIPIN antibody (CAB10344) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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