Anti-THSD7A Antibody (CAB16610)
- SKU:
- CAB16610
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
| 抗体名: | Anti-THSD7A Antibody |
| 抗体コード: | CAB16610 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 48-350 of human THSD7A (NP_056019.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | 293T |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 48-350 of human THSD7A (NP_056019.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AAQG EAEA PTLY LWKT GPWG RCMG DECG PGGI QTRA VWCA HVEG WTTL HTNC KQAE RPNN QQNC FKVC DWHK ELYD WRLG PWNQ CQPV ISKS LEKP LECI KGEE GIQV REIA CIQK DKDI PAED IICE YFEP KPLL EQAC LIPC QQDC IVSE FSAW SECS KTCG SGLQ HRTR HVVA PPQF GGSG CPNL TEFQ VCQS SPCE AEEL RYSL HVGP WSTC SMPH SRQV RQAR RRGK NKER EKDR SKGV KDPE AREL IKKK RNRN RQNR QENK YWDI QIGY QTRE VMCI NKTG KAAD LSFC QQEK LPM |
| 遺伝子ID: | 221981 |
| Uniprot: | Q9UPZ6 |
| セルラーロケーション: | Cell membrane, Secreted, Single-pass type I membrane protein |
| 計算された分子量: | 185kDa |
| 観察された分子量: | 260kDa |
| 同義語: | THSD7A |
| バックグラウンド: | The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis. |
| UniProt Protein Function: | THSD7A: The soluble form promotes endothelial cell migration and filopodia formationduring angiogenesis via a FAK-dependent mechanism. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 7p21.3 |
| NCBI Summary: | The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis. [provided by RefSeq, Aug 2010] |
| UniProt Code: | Q9UPZ6 |
| NCBI GenInfo Identifier: | 296453024 |
| NCBI Gene ID: | 221981 |
| NCBI Accession: | Q9UPZ6.4 |
| UniProt Related Accession: | Q9UPZ6 |
| Molecular Weight: | 185,363 Da |
| NCBI Full Name: | Thrombospondin type-1 domain-containing protein 7A |
| NCBI Synonym Full Names: | thrombospondin type 1 domain containing 7A |
| NCBI Official Symbol: | THSD7A |
| NCBI Protein Information: | thrombospondin type-1 domain-containing protein 7A |
| UniProt Protein Name: | Thrombospondin type-1 domain-containing protein 7A |
| Protein Family: | Thrombospondin type-1 domain-containing protein |
| UniProt Gene Name: | THSD7A |
 | Western blot analysis of extracts of 293T cells, using THSD7A antibody (CAB16610) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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