Anti-THSD4 Antibody (CAB17773)
- SKU:
- CAB17773
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-THSD4 Antibody |
抗体コード: | CAB17773 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human THSD4 (NP_079093.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | SH-SY5Y |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human THSD4 (NP_079093.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | AEGP TNEI LDVY MIHQ QPNP GVHY EYVI MGTN AISP QVPP HRRP GEPF NGQM VTEG RSQE EGEQ KGRN EEKE DLRG EAPE MFTS ESAQ TFPV RHPD RFSP HRPD NLVP PAPQ PPRR SRDH NWKQ LGTT ECST TCGK GSQY PIFR CVHR STHE EAPE SYCD SSMK PTPE EEPC NIFP CPAF WDIG EWSE CSKT CGLG MQHR Q |
遺伝子ID: | 79875 |
Uniprot: | Q6ZMP0 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | 112kDa |
同義語: | ADAMTSL-6, ADAMTSL6, FVSY9334, PRO34005, THSD4 |
バックグラウンド: |
UniProt Protein Function: | THSD4: Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Protease; Secreted; Extracellular matrix; Secreted, signal peptide Chromosomal Location of Human Ortholog: 15q23 Cellular Component: microfibril Molecular Function:metalloendopeptidase activity Biological Process: elastic fiber assembly; proteolysis |
UniProt Code: | Q6ZMP0 |
NCBI GenInfo Identifier: | 556695454 |
NCBI Gene ID: | 79875 |
NCBI Accession: | NP_001273358.1 |
UniProt Secondary Accession: | Q6ZMP0,Q6MZI3, Q6UXZ8, Q9H8E4, B2RTY3, B4DR13, |
UniProt Related Accession: | Q6ZMP0 |
Molecular Weight: | 73,408 Da |
NCBI Full Name: | thrombospondin type-1 domain-containing protein 4 isoform 2 |
NCBI Synonym Full Names: | thrombospondin, type I, domain containing 4 |
NCBI Official Symbol: | THSD4 |
NCBI Official Synonym Symbols: | ADAMTSL6; FVSY9334; PRO34005; ADAMTSL-6 |
NCBI Protein Information: | thrombospondin type-1 domain-containing protein 4 |
UniProt Protein Name: | Thrombospondin type-1 domain-containing protein 4 |
UniProt Synonym Protein Names: | A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6; ADAMTS-like protein 6; ADAMTSL-6 |
Protein Family: | Thrombospondin type-1 domain-containing protein |
UniProt Gene Name: | THSD4 |
UniProt Entry Name: | THSD4_HUMAN |