Anti-Thioredoxin 2 Antibody (CAB4424)
- SKU:
- CAB4424
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-Thioredoxin 2 Antibody |
抗体コード: | CAB4424 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human Thioredoxin 2 |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2, BxPC-3, Jurkat, Mouse liver, Mouse brain, Mouse spleen, Rat liver, Rat kidney |
免疫原: | A synthesized peptide derived from human Thioredoxin 2 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 25828 |
Uniprot: | Q99757 |
セルラーロケーション: | |
計算された分子量: | 12kDa |
観察された分子量: | 13KDa |
同義語: | COXPD29, MT-TRX, MTRX, TRX2, TXN |
バックグラウンド: | This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008] |
UniProt Protein Function: | TXN2: Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity. Belongs to the thioredoxin family. |
UniProt Protein Details: | Protein type:Oxidoreductase Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: cell soma; mitochondrion; mitochondrial matrix; dendrite; nucleolus Molecular Function:peptide-methionine-(S)-S-oxide reductase activity; protein complex binding; protein disulfide oxidoreductase activity; peptide-methionine (R)-S-oxide reductase activity Biological Process: response to drug; cellular response to nutrient levels; response to reactive oxygen species; cell redox homeostasis; response to hormone stimulus; response to glucose stimulus; response to hypoxia; response to axon injury; response to organic cyclic substance; glycerol ether metabolic process; response to nutrient |
NCBI Summary: | This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99757 |
NCBI GenInfo Identifier: | 20455529 |
NCBI Gene ID: | 25828 |
NCBI Accession: | Q99757.2 |
UniProt Secondary Accession: | Q99757,Q5JZA0, Q6FH60, Q9UH29, |
UniProt Related Accession: | Q99757 |
Molecular Weight: | |
NCBI Full Name: | Thioredoxin, mitochondrial |
NCBI Synonym Full Names: | thioredoxin 2 |
NCBI Official Symbol: | TXN2 |
NCBI Official Synonym Symbols: | MTRX; TRX2; MT-TRX |
NCBI Protein Information: | thioredoxin, mitochondrial; thioredoxin-2; mitochondrial thioredoxin |
UniProt Protein Name: | Thioredoxin, mitochondrial |
UniProt Synonym Protein Names: | Thioredoxin-2 |
UniProt Gene Name: | TXN2 |
UniProt Entry Name: | THIOM_HUMAN |
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