Anti-TGFBI Antibody (CAB2407)
- SKU:
- CAB2407
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| 抗体名: | Anti-TGFBI Antibody |
| 抗体コード: | CAB2407 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human TGFBI |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse liver, Mouse heart, Rat testis, Rat kidney |
| 免疫原: | A synthesized peptide derived from human TGFBI |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 7045 |
| Uniprot: | Q15582 |
| セルラーロケーション: | |
| 計算された分子量: | 68kDa |
| 観察された分子量: | 66KDa |
| 同義語: | BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, LCD1 |
| バックグラウンド: | This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | betaIG-H3: Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation. By TGFB1. Highly expressed in the corneal epithelium. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Cell adhesion; Secreted; Extracellular matrix Chromosomal Location of Human Ortholog: 5q31 Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; extracellular region; plasma membrane; basement membrane; trans-Golgi network Molecular Function:collagen binding; integrin binding; protein binding; extracellular matrix binding Biological Process: cell proliferation; extracellular matrix organization and biogenesis; visual perception; response to stimulus; chondrocyte differentiation; negative regulation of cell adhesion; angiogenesis; cell adhesion Disease: Corneal Dystrophy, Epithelial Basement Membrane; Corneal Dystrophy, Lattice Type Iiia; Corneal Dystrophy, Avellino Type; Corneal Dystrophy Of Bowman Layer, Type Ii; Corneal Dystrophy, Lattice Type I; Corneal Dystrophy Of Bowman Layer, Type I; Corneal Dystrophy, Groenouw Type I |
| NCBI Summary: | This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15582 |
| NCBI GenInfo Identifier: | 2498193 |
| NCBI Gene ID: | 7045 |
| NCBI Accession: | Q15582.1 |
| UniProt Secondary Accession: | Q15582,O14471, O14472, O14476, O43216, O43217, O43218 O43219, Q53XM1, D3DQB1, |
| UniProt Related Accession: | Q15582 |
| Molecular Weight: | 74,681 Da |
| NCBI Full Name: | Transforming growth factor-beta-induced protein ig-h3 |
| NCBI Synonym Full Names: | transforming growth factor, beta-induced, 68kDa |
| NCBI Official Symbol: | TGFBI |
| NCBI Official Synonym Symbols: | CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1 |
| NCBI Protein Information: | transforming growth factor-beta-induced protein ig-h3; RGD-CAP; beta ig-h3; kerato-epithelin; RGD-containing collagen-associated protein; transforming growth factor, beta-induced, 68kD |
| UniProt Protein Name: | Transforming growth factor-beta-induced protein ig-h3 |
| UniProt Synonym Protein Names: | Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP |
| Protein Family: | Transforming growth factor-beta-induced protein |
| UniProt Gene Name: | TGFBI |
| UniProt Entry Name: | BGH3_HUMAN |
 | Western blot - TGFBI Rabbit mAb (CAB2407) |