Anti-TCF4 Antibody (CAB12017)
- SKU:
- CAB12017
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-TCF4 Antibody |
抗体コード: | CAB12017 |
抗体サイズ: | 20uL, 50 uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 291-540 of mouse TCF4 (NP_038713.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 291-540 of mouse TCF4 (NP_038713.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | STSS CTPP ANGT DSIM ANRG TGAA GSSQ TGDA LGKA LASI YSPD HTNN SFSS NPST PVGS PPSL SAGT AVWS RNGG QASS SPNY EGPL HSLQ SRIE DRLE RLDD AIHV LRNH AVGP STAV PGGH GDMH GIMG PSHN GAMG SLGS GYGT SLLS ANRH SLMV GAHR EDGV ALRG SHSL LPNQ VPVP QLPV QSAT SPDL NPPQ DPYR GMPP GLQG QSVS SGSS EIKS DDEG DENL QDTK SSED KKLD DDKK DI |
遺伝子ID: | 21413 |
Uniprot: | |
セルラーロケーション: | Nucleus |
計算された分子量: | 54kDa/71kDa |
観察された分子量: | 85kDa |
同義語: | TCF4, E2-2, FECD3, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, SEF2-1D, TCF-4, bHLHb19, 5730422P05Rik, ASP-I2, E2.2, ITF-2b, ME2, MITF-2A, MITF-2B, TFE, Tcf-4 |
バックグラウンド: | This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. |