Anti-TCERG1 Antibody (CAB14850)
- SKU:
- CAB14850
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-TCERG1 Antibody |
抗体コード: | CAB14850 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TCERG1 (NP_006697.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | HeLa, Jurkat, SW480 |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TCERG1 (NP_006697.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | TTRL SMWD RPDD LIGR ADVD KIIQ EPPH KKGM EELK KLRH PTPT MLSI QKWQ FSMS AIKE EQEL MEEI NEDE PVKA KKRK RDDN KDID SEKE AAME AEIK A |
遺伝子ID: | 10915 |
Uniprot: | O14776 |
セルラーロケーション: | Nucleus |
計算された分子量: | 121kDa/123kDa |
観察された分子量: | 160kDa |
同義語: | TCERG1, CA150, TAF2S, Urn1 |
バックグラウンド: | This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. |
UniProt Protein Function: | TCERG1: Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Spliceosome; Transcription factor; RNA-binding Chromosomal Location of Human Ortholog: 5q31 Cellular Component: actin cytoskeleton; nucleolus; nucleus Molecular Function:protein binding; transcription coactivator activity Biological Process: negative regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter |
NCBI Summary: | This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
UniProt Code: | O14776 |
NCBI GenInfo Identifier: | 158514955 |
NCBI Gene ID: | 10915 |
NCBI Accession: | O14776.2 |
UniProt Secondary Accession: | O14776,Q2NKN2, Q59EA1, |
UniProt Related Accession: | O14776 |
Molecular Weight: | 121,690 Da |
NCBI Full Name: | Transcription elongation regulator 1 |
NCBI Synonym Full Names: | transcription elongation regulator 1 |
NCBI Official Symbol: | TCERG1 |
NCBI Official Synonym Symbols: | Urn1; CA150; TAF2S |
NCBI Protein Information: | transcription elongation regulator 1 |
UniProt Protein Name: | Transcription elongation regulator 1 |
UniProt Synonym Protein Names: | TATA box-binding protein-associated factor 2S; Transcription factor CA150 |
Protein Family: | Transcription elongation regulator |
UniProt Gene Name: | TCERG1 |
UniProt Entry Name: | TCRG1_HUMAN |
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