Anti-TCEA1 Antibody (CAB10541)
- SKU:
- CAB10541
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-TCEA1 Antibody |
| 抗体コード: | CAB10541 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human TCEA1 (NP_006747.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-87MG, 293T, Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human TCEA1 (NP_006747.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PSTE KDLD EKKK EPAI TSQN SPEA REES TSSG NVSN RKDE TNAR DTYV SSFP RAPS TSDS VRLK CREM LAAA LRTG DDYI AIGA DEEE LGSQ IEEA IYQE I |
| 遺伝子ID: | 6917 |
| Uniprot: | P23193 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 31kDa/33kDa |
| 観察された分子量: | 38kDa |
| 同義語: | TCEA1, GTF2S, SII, TCEA, TF2S, TFIIS |
| バックグラウンド: |
| UniProt Protein Function: | TFIIS: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. A chromosomal aberration involving TCEA1 may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(3;8)(p21;q12) with PLAG1. Belongs to the TFS-II family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription factor Chromosomal Location of Human Ortholog: 8q11.23 Cellular Component: nucleolus; nucleoplasm; nucleus; transcription factor TFIID complex Molecular Function:protein binding Biological Process: RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair |
| UniProt Code: | P23193 |
| NCBI GenInfo Identifier: | 1174652 |
| NCBI Gene ID: | 6917 |
| NCBI Accession: | P23193.2 |
| UniProt Secondary Accession: | P23193,Q15563, Q6FG87, A6NF25, A8K339, |
| UniProt Related Accession: | P23193 |
| Molecular Weight: | 34kDa |
| NCBI Full Name: | Transcription elongation factor A protein 1 |
| NCBI Synonym Full Names: | transcription elongation factor A1 |
| NCBI Official Symbol: | TCEA1 |
| NCBI Official Synonym Symbols: | SII; TCEA; TF2S; GTF2S; TFIIS |
| NCBI Protein Information: | transcription elongation factor A protein 1 |
| UniProt Protein Name: | Transcription elongation factor A protein 1 |
| UniProt Synonym Protein Names: | Transcription elongation factor S-II protein 1; Transcription elongation factor TFIIS.o |
| Protein Family: | Tuliposide A-converting enzyme |
| UniProt Gene Name: | TCEA1 |
 | Western blot analysis of extracts of various cell lines, using TCEA1 antibody (CAB10541) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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