Anti-TBXA2R Antibody (CAB8458)
- SKU:
- CAB8458
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TBXA2R Antibody |
| 抗体コード: | CAB8458 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 229-343 of human TBXA2R (NP_001051.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | A-549, HeLa, HepG2, K-562, Mouse lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 229-343 of human TBXA2R (NP_001051.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | QEAA QQRP RDSE VEMM AQLL GIMV VASV CWLP LLVF IAQT VLRN PPAM SPAG QLSR TTEK ELLI YLRV ATWN QILD PWVY ILFR RAVL RRLQ PRLS TRPR SLSL QPQL TQRS GLQ |
| 遺伝子ID: | 6915 |
| Uniprot: | P21731 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 37kDa/44kDa |
| 観察された分子量: | 45kDa |
| 同義語: | TBXA2R, BDPLT13, TXA2-R |
| バックグラウンド: | This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase. |
| NCBI Summary: | This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
| UniProt Code: | P21731 |
| NCBI GenInfo Identifier: | 4507381 |
| NCBI Gene ID: | 6915 |
| NCBI Accession: | NP_001051.1 |
| UniProt Secondary Accession: | P21731,O75228, Q6DK52, Q9UCY1, Q9UCY2, |
| UniProt Related Accession: | P21731 |
| Molecular Weight: | |
| NCBI Full Name: | thromboxane A2 receptor isoform alpha |
| NCBI Synonym Full Names: | thromboxane A2 receptor |
| NCBI Official Symbol: | TBXA2R |
| NCBI Official Synonym Symbols: | TXA2-R; BDPLT13 |
| NCBI Protein Information: | thromboxane A2 receptor |
| UniProt Protein Name: | Thromboxane A2 receptor |
| UniProt Synonym Protein Names: | Prostanoid TP receptor |
| Protein Family: | Trehalose phosphorylase |
| UniProt Gene Name: | TBXA2R |
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