| UniProt Protein Function: | TBR1: Probable transcriptional regulator involved in developmental processes. TBR1 is required for normal brain development. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 2q24 Biological Process: brain development |
| NCBI Summary: | This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015] |
| UniProt Code: | Q16650 |
| NCBI GenInfo Identifier: | 2501122 |
| NCBI Gene ID: | 10716 |
| NCBI Accession: | Q16650.1 |
| UniProt Secondary Accession: | Q16650,Q14DC5, Q53TH0, Q56A81, B0AZS4, B2R6G5, |
| UniProt Related Accession: | Q16650 |
| Molecular Weight: | 42,332 Da |
| NCBI Full Name: | T-box brain protein 1 |
| NCBI Synonym Full Names: | T-box, brain 1 |
| NCBI Official Symbol: | TBR1 |
| NCBI Official Synonym Symbols: | TBR-1; TES-56 |
| NCBI Protein Information: | T-box brain protein 1 |
| UniProt Protein Name: | T-box brain protein 1 |
| UniProt Synonym Protein Names: | TES-56 |
| Protein Family: | T-box protein |
| UniProt Gene Name: | TBR1 |
| UniProt Entry Name: | TBR1_HUMAN |
