Anti-TBPL1 Antibody (CAB7575)
- SKU:
- CAB7575
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-TBPL1 Antibody |
抗体コード: | CAB7575 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-186 of human TBPL1 (NP_004856.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-186 of human TBPL1 (NP_004856.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MDAD SDVA LDIL ITNV VCVF RTRC HLNL RKIA LEGA NVIY KRDV GKVL MKLR KPRI TATI WSSG KIIC TGAT SEEE AKFG ARRL ARSL QKLG FQVI FTDF KVVN VLAV CNMP FEIR LPEF TKNN RPHA SYEP ELHP AVCY RIKS LRAT LQIF STGS ITVT GPNV KAVA TAVE QIYP FVFE SRKE IL |
遺伝子ID: | 9519 |
Uniprot: | P62380 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 20kDa |
観察された分子量: | 21kDa |
同義語: | TBPL1, MGC:8389, MGC:9620, STUD, TLF, TLP, TRF2 |
バックグラウンド: | This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. |
UniProt Protein Function: | TBPL1: Does not bind the TATA box. Has DNA-binding ability. Belongs to the TBP family. |
UniProt Protein Details: | Protein type:Cell development/differentiation; DNA-binding; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 6q23.2 Cellular Component: cytoplasm; transcription factor TFIIA complex Molecular Function:DNA binding; transcription coactivator activity Biological Process: acrosome formation; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription initiation; spermatid nuclear differentiation; dTTP biosynthetic process |
NCBI Summary: | This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Nov 2011] |
UniProt Code: | P62380 |
NCBI GenInfo Identifier: | 358439409 |
NCBI Gene ID: | 9519 |
NCBI Accession: | NP_001240605 |
UniProt Related Accession: | P62380 |
Molecular Weight: | |
NCBI Full Name: | TATA box-binding protein-like protein 1 |
NCBI Synonym Full Names: | TATA-box binding protein like 1 |
NCBI Official Symbol: | TBPL1 |
NCBI Official Synonym Symbols: | TLF; TLP; STUD; TRF2; MGC:8389; MGC:9620 |
NCBI Protein Information: | TATA box-binding protein-like protein 1 |
UniProt Protein Name: | TATA box-binding protein-like protein 1 |
UniProt Synonym Protein Names: | 21 kDa TBP-like protein; Second TBP of unique DNA protein; STUD; TATA box-binding protein-related factor 2; TBP-related factor 2; TBP-like factor; TBP-related protein |
Protein Family: | Protein |
UniProt Gene Name: | TBPL1 |
UniProt Entry Name: | TBPL1_HUMAN |
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