Anti-TBL2 Antibody (CAB15429)
- SKU:
- CAB15429
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TBL2 Antibody |
| 抗体コード: | CAB15429 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-430 of human TBL2 (NP_036585.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | LO2, 293T, HeLa, Mouse brain, Rat pancreas |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-430 of human TBL2 (NP_036585.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SNGK YLAT CADD RTIR IWST KDFL QREH RSMR ANVE LDHA TLVR FSPD CRAF IVWL ANGD TLRV FKMT KRED GGYT FTAT PEDF PKKH KAPV IDIG IANT GKFI MTAS SDTT VLIW SLKG QVLS TINT NQMN NTHA AVSP CGRF VASC GFTP DVKV WEVC FGKK GEFQ EVVR AFEL KGHS AAVH SFAF SNDS RRMA SVSK DGTW KLWD TDVE YKKK QDPY LLKT GRFE EAAG AAPC RLAL SPNA QVLA LASG SSIH LYNT RRGE KEEC FERV HGEC IANL SFDI TGRF LASC GDRA VRLF HNTP GHRA MVEE MQGH LKRA SNES TRQR LQQ |
| 遺伝子ID: | 26608 |
| Uniprot: | Q9Y4P3 |
| セルラーロケーション: | |
| 計算された分子量: | 49kDa |
| 観察された分子量: | 50kDa |
| 同義語: | TBL2, WBSCR13, WS-betaTRP |
| バックグラウンド: | This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23. |
| UniProt Protein Function: | TBL2: TBL2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of TBL2 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 7q11.23 Cellular Component: endoplasmic reticulum; integral to endoplasmic reticulum membrane Molecular Function:translation initiation factor binding; phosphoprotein binding; protein kinase binding Biological Process: cellular response to glucose starvation; unfolded protein response |
| UniProt Code: | Q9Y4P3 |
| NCBI GenInfo Identifier: | 12643953 |
| NCBI Gene ID: | |
| NCBI Accession: | Q9Y4P3.1 |
| Molecular Weight: | 50kDa |
| NCBI Full Name: | Transducin beta-like protein 2 |
| UniProt Protein Name: | Transducin beta-like protein 2 |
| UniProt Synonym Protein Names: | WS beta-transducin repeats protein; WS-betaTRP; Williams-Beuren syndrome chromosomal region 13 protein |
| Protein Family: | Transducin beta-like protein |
| UniProt Gene Name: | TBL2 |
| UniProt Entry Name: | TBL2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TBL2 antibody (CAB15429) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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