Anti-TACR3 Antibody (CAB7220)
- SKU:
- CAB7220
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-TACR3 Antibody |
抗体コード: | CAB7220 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 356-465 of human TACR3 (NP_001050.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HL-60, Human placenta |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 356-465 of human TACR3 (NP_001050.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | YCCL NKRF RAGF KRAF RWCP FIKV SSYD ELEL KTTR FHPN RQSS MYTV TRME SMTV VFDP NDAD TTRS SRKK RATP RDPS FNGC SRRN SKSA SATS SFIS SPYT SVDE YS |
遺伝子ID: | 6870 |
Uniprot: | P29371 |
セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
計算された分子量: | 52kDa |
観察された分子量: | 52kDa |
同義語: | TACR3, HH11, NK-3R, NK3R, NKR, TAC3RL |
バックグラウンド: | This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. |
UniProt Protein Function: | TACR3: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR Chromosomal Location of Human Ortholog: 4q25 Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; nucleus Molecular Function:protein binding; tachykinin receptor activity Biological Process: tachykinin signaling pathway; hyperosmotic salinity response; regulation of dopamine metabolic process; response to morphine; positive regulation of heart rate; response to cocaine; response to estradiol stimulus; positive regulation of blood pressure; aging Disease: Hypogonadotropic Hypogonadism 11 With Or Without Anosmia |
NCBI Summary: | This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008] |
UniProt Code: | P29371 |
NCBI GenInfo Identifier: | 128364 |
NCBI Gene ID: | 6870 |
NCBI Accession: | P29371.1 |
UniProt Secondary Accession: | P29371,Q0P510, |
UniProt Related Accession: | P29371 |
Molecular Weight: | Calculated: 52kDaObserved: 50kDa |
NCBI Full Name: | Neuromedin-K receptor |
NCBI Synonym Full Names: | tachykinin receptor 3 |
NCBI Official Symbol: | TACR3 |
NCBI Official Synonym Symbols: | NKR; HH11; NK3R; NK-3R; TAC3RL |
NCBI Protein Information: | neuromedin-K receptor; NK-3 receptor; neurokinin B receptor; neurokinin beta receptor |
UniProt Protein Name: | Neuromedin-K receptor |
UniProt Synonym Protein Names: | NK-3 receptor; NK-3R; Neurokinin B receptor; Tachykinin receptor 3 |
Protein Family: | Neuromedin-K receptor |
UniProt Gene Name: | TACR3 |
UniProt Entry Name: | NK3R_HUMAN |
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