Anti-TAC3 Antibody (CAB6312)
- SKU:
- CAB6312
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-TAC3 Antibody |
| 抗体コード: | CAB6312 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human TAC3 (NP_037383.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:10 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Jurkat, Mouse spleen, Mouse brain, Rat kidney, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human TAC3 (NP_037383.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MRIM LLFT AILA FSLA QSFG AVCK EPQE EVVP GGGR SKRD PDLY QLLQ RLFK SHSS LEGL LKAL SQAS TDPK ESTS PEKR DMHD FFVG LMGK RSVQ PDSP TDVN QENV PSFG ILKY PPRA E |
| 遺伝子ID: | 6866 |
| Uniprot: | Q9UHF0 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 11kDa/13kDa/14kDa |
| 観察された分子量: | 16kDa |
| 同義語: | TAC3, HH10, NKB, NKNB, PRO1155, ZNEUROK1 |
| バックグラウンド: | This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded preproprotein is proteolytically processed to generate the mature peptide, which is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. This peptide is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| UniProt Protein Function: | TAC3: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 12q13.3 Cellular Component: extracellular region; extracellular space Molecular Function:receptor binding Biological Process: female pregnancy Disease: Hypogonadotropic Hypogonadism 10 With Or Without Anosmia |
| NCBI Summary: | This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded preproprotein is proteolytically processed to generate the mature peptide, which is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. This peptide is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
| UniProt Code: | Q9UHF0 |
| NCBI GenInfo Identifier: | 18203501 |
| NCBI Gene ID: | 6866 |
| NCBI Accession: | Q9UHF0.1 |
| UniProt Secondary Accession: | Q9UHF0,Q6IAG2, Q71BC6, Q71BC9, |
| UniProt Related Accession: | Q9UHF0 |
| Molecular Weight: | 11,358 Da |
| NCBI Full Name: | Tachykinin-3 |
| NCBI Synonym Full Names: | tachykinin 3 |
| NCBI Official Symbol: | TAC3 |
| NCBI Official Synonym Symbols: | NKB; HH10; NKNB; PRO1155; ZNEUROK1 |
| NCBI Protein Information: | tachykinin-3 |
| UniProt Protein Name: | Tachykinin-3 |
| UniProt Synonym Protein Names: | ZNEUROK1 |
| Protein Family: | Tachykinin |
| UniProt Gene Name: | TAC3 |
| UniProt Entry Name: | TKNK_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TAC3 antibody (CAB6312) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 20s. |
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