Anti-TAC1 Antibody (CAB13550)
- SKU:
- CAB13550
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| 抗体名: | Anti-TAC1 Antibody |
| 抗体コード: | CAB13550 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IF |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human TAC1 (NP_003173.1). |
| 申し込み: | IF |
| 推奨希釈: | IF 1:50 - 1:200 |
| 反応性: | Human, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human TAC1 (NP_003173.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MKIL VALA VFFL VSTQ LFAE EIGA NDDL NYWS DWYD SDQI KEEL PEPF EHLL QRIA RRPK PQQF FGLM GKRD ADSS IEKQ VALL KALY GHGQ ISHK RHKT DSFV GLMG KRAL NSVA YERS AMQN YERR R |
| 遺伝子ID: | 6863 |
| Uniprot: | P20366 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 11kDa/13kDa/15kDa |
| 観察された分子量: |
| 同義語: | TAC1, Hs.2563, NK2, NKNA, NPK, TAC2 |
| バックグラウンド: | This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | TAC1: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 7q21-q22 Cellular Component: extracellular space; cell soma; axon; extracellular region; plasma membrane Molecular Function:protein binding; substance P receptor binding Biological Process: tachykinin signaling pathway; negative regulation of heart rate; insemination; response to hormone stimulus; response to morphine; response to lipopolysaccharide; response to pain; sensory perception of pain; positive regulation of saliva secretion; synaptic transmission; elevation of cytosolic calcium ion concentration; cell-cell signaling; positive regulation of acute inflammatory response; positive regulation of lymphocyte proliferation; neuropeptide signaling pathway; regulation of blood pressure; positive regulation of stress fiber formation; positive regulation of action potential; inflammatory response; associative learning; detection of abiotic stimulus; positive regulation of synaptic transmission, cholinergic; positive regulation of synaptic transmission, GABAergic; positive regulation of ossification; long-term memory |
| NCBI Summary: | This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014] |
| UniProt Code: | P20366 |
| NCBI GenInfo Identifier: | 135886 |
| NCBI Gene ID: | 6863 |
| NCBI Accession: | P20366.1 |
| UniProt Related Accession: | P20366 |
| Molecular Weight: | |
| NCBI Full Name: | Protachykinin-1 |
| NCBI Synonym Full Names: | tachykinin precursor 1 |
| NCBI Official Symbol: | TAC1 |
| NCBI Official Synonym Symbols: | NK2; NPK; NKNA; TAC2; Hs.2563 |
| NCBI Protein Information: | protachykinin-1 |
| UniProt Protein Name: | Protachykinin-1 |
| UniProt Synonym Protein Names: | PPTCleaved into the following 5 chains:Substance P; Neurokinin A; NKAAlternative name(s):Neuromedin L; Substance K |
| Protein Family: | Splenin |
| UniProt Gene Name: | TAC1 |
| UniProt Entry Name: | TKN1_HUMAN |
 | Immunofluorescence analysis of C6 cells using TAC1 antibody (CAB13550) at dilution of 1:100. Blue: DAPI for nuclear staining. |