Anti-SYT5 Antibody (CAB15321)
- SKU:
- CAB15321
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SYT5 Antibody |
| 抗体コード: | CAB15321 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SYT5 (NP_003171.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SYT5 (NP_003171.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MFPE PPTP GPPS PDTP PDSS RISH GPVP PWAL ATIV LVSG LLIF SCCF CLYR KSCR RRTG KKSQ AQAQ VHLQ EVKG LGQS YIDK VQPE VEEL EPAP SGPG QQVA DKHE LG |
| 遺伝子ID: | 6861 |
| Uniprot: | O00445 |
| セルラーロケーション: | Cytoplasmic vesicle, Recycling endosome membrane, Single-pass membrane protein, secretory vesicle, synaptic vesicle membrane |
| 計算された分子量: | 42kDa |
| 観察された分子量: | 43kDa |
| 同義語: | SYT5 |
| バックグラウンド: |
| UniProt Protein Function: | SYT5: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)- dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface. Belongs to the synaptotagmin family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.42|11p Cellular Component: plasma membrane; synaptic vesicle membrane Molecular Function:calcium ion binding; calcium-dependent phospholipid binding; clathrin binding; syntaxin binding Biological Process: calcium ion-dependent exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis; synaptic transmission; synaptic vesicle endocytosis; vesicle fusion |
| NCBI Summary: | Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).[supplied by OMIM, Feb 2011] |
| UniProt Code: | O00445 |
| NCBI GenInfo Identifier: | 32700066 |
| NCBI Gene ID: | 6861 |
| NCBI Accession: | O00445.2 |
| UniProt Secondary Accession: | O00445,Q86X72, B3KWJ8, B7Z300, |
| UniProt Related Accession: | O00445 |
| Molecular Weight: | 42,474 Da |
| NCBI Full Name: | Synaptotagmin-5 |
| NCBI Synonym Full Names: | synaptotagmin 5 |
| NCBI Official Symbol: | SYT5 |
| NCBI Protein Information: | synaptotagmin-5 |
| UniProt Protein Name: | Synaptotagmin-5 |
| UniProt Synonym Protein Names: | Synaptotagmin V; SytV |
| Protein Family: | Synaptotagmin |
| UniProt Gene Name: | SYT5 |
| UniProt Entry Name: | SYT5_HUMAN |
 | Western blot analysis of extracts of Mouse kidney, using SYT5 antibody (CAB15321) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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