Anti-Syntaxin-7 Antibody (CAB8057)
- SKU:
- CAB8057
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | STX7 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8057 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human STX7 (NP_003560.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-251MG, Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human STX7 (NP_003560.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSYT PGVG GDPA QLAQ RISS NIQK ITQC SVEI QRTL NQLG TPQD SPEL RQQL QQKQ QYTN QLAK ETDK YIKE FGSL PTTP SEQR QRKI QKDR LVAE FTTS LTNF QKVQ RQAA EREK EFVA RVRA SSRV SGSF PEDS SKER NLVS WESQ TQPQ VQVQ DEEI TEDD LRLI HE |
| 遺伝子ID: | 8417 |
| Uniprot: | O15400 |
| セルラーロケーション: | Early endosome membrane, Single-pass type IV membrane protein |
| 計算された分子量: | 27kDa/29kDa |
| 観察された分子量: | 40kDa |
| 同義語: | STX7 |
| バックグラウンド: | The protein encoded by this gene is a syntaxin family membrane receptor involved in vesicle transport. The encoded protein binds alpha-SNAP, an important regulator of transport vesicle fusion. Along with syntaxin 13, this protein plays a role in the ordered fusion of endosomes and lysosomes with the phagosome. |
| UniProt Protein Function: | STX7: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes. Belongs to the syntaxin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Vesicle; Membrane protein, integral Chromosomal Location of Human Ortholog: 6q23.1 Cellular Component: intracellular membrane-bound organelle; lysosomal membrane; lysosome; early endosome; integral to membrane; immunological synapse; endomembrane system; SNARE complex; azurophil granule; recycling endosome; endocytic vesicle; perinuclear region of cytoplasm; early endosome membrane; late endosome; plasma membrane; vesicle; endosome Molecular Function:SNAP receptor activity; SNARE binding; chloride channel inhibitor activity; syntaxin binding Biological Process: vesicle fusion; intracellular protein transport; organelle localization; vesicle docking; positive regulation of T cell mediated cytotoxicity |
| UniProt Code: | O15400 |
| NCBI GenInfo Identifier: | 20532414 |
| NCBI Gene ID: | 8417 |
| NCBI Accession: | O15400.4 |
| UniProt Secondary Accession: | O15400,O70439, |
| UniProt Related Accession: | O15400 |
| Molecular Weight: | 261 |
| NCBI Full Name: | Syntaxin-7 |
| NCBI Synonym Full Names: | syntaxin 7 |
| NCBI Official Symbol: | STX7 |
| NCBI Protein Information: | syntaxin-7 |
| UniProt Protein Name: | Syntaxin-7 |
| Protein Family: | Syntaxin |
| UniProt Gene Name: | STX7 |
| UniProt Entry Name: | STX7_HUMAN |
 | Western blot analysis of extracts of various cell lines, using STX7 antibody (CAB8057) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human stomach using STX7 antibody (CAB8057) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse kidney using STX7 antibody (CAB8057) at dilution of 1:100 (40x lens). |
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