Anti-SYNPO Antibody (CAB12049)
- SKU:
- CAB12049
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SYNPO Antibody |
| 抗体コード: | CAB12049 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human SYNPO (NP_001159680.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human SYNPO (NP_001159680.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MLGP HLPP PPLA PSEG RPTP CAFQ IPDG SYRC LALE AEES SGEE GLQG EVGP TDLE EDEG VSRS GDDS ACRV TQGT PQLP KALG IQPP SCSR EEQG ASQH DDRA SQDW DVVK AGQM MTAS PSPG PGPR VAQK PALG RSTS LTEK DLKE AKAR SQQI AAQL TTPP SSNS RGVQ LFNR RRQR VNEF TLES HGQR GQKP SQES LRVL PSSL PGHA PGLS LSST SLPE PGPP RHPS PQSP DRGV PGHS MEGY SEEA SLLR HLEK |
| 遺伝子ID: | 11346 |
| Uniprot: | Q8N3V7 |
| セルラーロケーション: | Cell junction, Cell projection, Cytoplasm, Perikaryon, cytoskeleton, dendritic spine, postsynaptic cell membrane, postsynaptic density, synapse, tight junction |
| 計算された分子量: | 73kDa/96kDa/99kDa |
| 観察された分子量: | 115kDa |
| 同義語: | SYNPO |
| バックグラウンド: |
| UniProt Protein Function: | SYNPO: an actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity. |
| UniProt Protein Details: | Protein type:Actin-binding; Cytoskeletal Chromosomal Location of Human Ortholog: 5q33.1 Cellular Component: actin cytoskeleton; dendritic spine Molecular Function:actin binding; protein binding |
| NCBI Summary: | Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8N3V7 |
| NCBI GenInfo Identifier: | 48428650 |
| NCBI Gene ID: | 11346 |
| NCBI Accession: | Q8N3V7.2 |
| UniProt Secondary Accession: | Q8N3V7,O15271, Q9UPX1, A5PKZ8, D3DQG8, |
| UniProt Related Accession: | Q8N3V7 |
| Molecular Weight: | 73,667 Da |
| NCBI Full Name: | Synaptopodin |
| NCBI Synonym Full Names: | synaptopodin |
| NCBI Official Symbol: | SYNPO |
| NCBI Protein Information: | synaptopodin |
| UniProt Protein Name: | Synaptopodin |
| Protein Family: | Synaptopodin |
| UniProt Gene Name: | SYNPO |
| UniProt Entry Name: | SYNPO_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SYNPO antibody (CAB12049) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 5s. |
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