Anti-Symplekin Antibody (CAB8722)
- SKU:
- CAB8722
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-Symplekin Antibody |
| 抗体コード: | CAB8722 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 310-530 of human SYMPK (NP_004810.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | LO2, 293T, HL-60, HT-1080, A-549, Mouse brain, Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 310-530 of human SYMPK (NP_004810.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | KHPA SLEF QAQI TTLL VDLG TPQA EIAR NMPS SKDT RKRP RDDS DSTL KKMK LEPN LGED DEDK DLEP GPSG TSKA SAQI SGQS DTDI TAEF LQPL LTPD NVAN LVLI SMVY LPEA MPAS FQAI YTPV ESAG TEAQ IKHL ARLM ATQM TAAG LGPG VEQT KQCK EEPK EEKV VKTE SVLI KRRL SAQG QAIS VVGS LSSM SPLE EEAP QAKR RPEP IIPV T |
| 遺伝子ID: | 8189 |
| Uniprot: | Q92797 |
| セルラーロケーション: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Nucleus, Peripheral membrane protein, cytoskeleton, nucleoplasm, tight junction |
| 計算された分子量: | 74kDa/141kDa |
| 観察された分子量: | 141kDa |
| 同義語: | SYMPK, SPK, SYM, symplekin |
| バックグラウンド: | This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. |
| NCBI Summary: | This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92797 |
| NCBI GenInfo Identifier: | 124028529 |
| NCBI Gene ID: | 8189 |
| NCBI Accession: | NP_004810.2 |
| UniProt Related Accession: | Q92797 |
| Molecular Weight: | 141kDa |
| NCBI Full Name: | symplekin |
| NCBI Synonym Full Names: | symplekin |
| NCBI Official Symbol: | SYMPK |
| NCBI Official Synonym Symbols: | SPK; SYM |
| NCBI Protein Information: | symplekin |
| UniProt Protein Name: | Symplekin |
| Protein Family: | Symplekin |
| UniProt Gene Name: | SYMPK |
| UniProt Entry Name: | SYMPK_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SYMPK antibody (CAB8722) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
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