Anti-SYCE1 Antibody (CAB7218)
- SKU:
- CAB7218
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-SYCE1 Antibody |
| 抗体コード: | CAB7218 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 132-351 of human SYCE1 (NP_001137236.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse liver, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 132-351 of human SYCE1 (NP_001137236.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | ECKE RISA LNLQ IEEE KNKQ RQLR LAFE EQLE DLMG QHKD LWDF HMPE RLAK EICA LDSS KEQL LKEE KLVK ATLE DVKH QLCS LCGA EGPS TLDE GLFL RSQE AAAT VQLF QEEH RKAE ELLA AAAQ RHQQ LQQK CQQQ QQKR QRLK EELE KHGM QVPA QAQS TQEE EAGP GDVA SPKP LKGE RPGA AHQA GPDV LIGQ EDTL HPDL SPRG FQEI KELF |
| 遺伝子ID: | 93426 |
| Uniprot: | Q8N0S2 |
| セルラーロケーション: | Chromosome, Nucleus |
| 計算された分子量: | 21kDa/32kDa/39kDa |
| 観察された分子量: | 40kDa |
| 同義語: | SYCE1, C10orf94, CT76, POF12, SPGF15 |
| バックグラウンド: | This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | SYCE1: Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination. Belongs to the SYCE family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA) Chromosomal Location of Human Ortholog: 10q26.3 Cellular Component: central element Biological Process: synaptonemal complex assembly; cell division |
| UniProt Code: | Q8N0S2 |
| NCBI GenInfo Identifier: | 118573896 |
| NCBI Gene ID: | 93426 |
| NCBI Accession: | Q8N0S2.2 |
| UniProt Secondary Accession: | Q8N0S2,Q9D495, Q5XHZ2, |
| UniProt Related Accession: | Q8N0S2 |
| Molecular Weight: | 351 |
| NCBI Full Name: | Synaptonemal complex central element protein 1 |
| NCBI Synonym Full Names: | synaptonemal complex central element protein 1 |
| NCBI Official Symbol: | SYCE1 |
| NCBI Official Synonym Symbols: | CT76; C10orf94 |
| NCBI Protein Information: | synaptonemal complex central element protein 1; cancer/testis antigen 76 |
| UniProt Protein Name: | Synaptonemal complex central element protein 1 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 76; CT76 |
| Protein Family: | Synaptonemal complex central element protein |
| UniProt Gene Name: | SYCE1 |
| UniProt Entry Name: | SYCE1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SYCE1 antibody (CAB7218) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of MCF-7 cells using SYCE1 antibody (CAB7218). Blue: DAPI for nuclear staining. |
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