Anti-SUPT6H Antibody (CAB16434)
- SKU:
- CAB16434
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
抗体名: | Anti-SUPT6H Antibody |
抗体コード: | CAB16434 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1500-1726 of human SUPT6H (NP_003161.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, Jurkat, HeLa, Mouse brain, Mouse heart, Mouse liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1500-1726 of human SUPT6H (NP_003161.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | IFPT VNGL FRWF KDHY QDPV PGIT PSSS SRTR TPAS INAT PANI NLAD LTRA VNAL PQNM TSQM FSAI AAVT GQGQ NPNA TPAQ WASS QYGY GGSG GGSS AYHV FPTP AQQP VATP LMTP SYSY TTPS QPIT TPQY HQLQ ASTT PQSA QAQP QPSS SSRQ RQQQ PKSN SHAA IDWG KMAE QWLQ EKEA ERRK QKQR LTPR PSPS PMIE STPM SIAG DATP LLDE MDR |
遺伝子ID: | 6830 |
Uniprot: | Q7KZ85 |
セルラーロケーション: | Nucleus |
計算された分子量: | 61kDa/84kDa/199kDa |
観察された分子量: | 260kDa |
同義語: | SUPT6H, SPT6, SPT6H, emb-5, SPT6 homolog |
バックグラウンド: |
UniProt Protein Function: | SPT6: promotes transcription elongation of many genes. A histone H3 chaperone that may alter chromatin structure during transcription. Binds RNA polymerase II (RNAPII) phosphorylated on Ser2 through its primitive SH2 domain, which appears to recognize phosphoserine rather than phosphotyrosine motifs. Associates with the nuclear mRNA export factor, THOC4. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; RNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 17q11.2 Molecular Function:histone binding; protein binding; transcription factor activity Biological Process: positive regulation of RNA elongation from RNA polymerase II promoter; regulation of isotype switching; regulation of mRNA processing; regulation of muscle cell differentiation |
UniProt Code: | Q7KZ85 |
NCBI GenInfo Identifier: | 51701986 |
NCBI Gene ID: | 6830 |
NCBI Accession: | Q7KZ85.2 |
UniProt Secondary Accession: | Q7KZ85,Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775 Q96AH3, Q9BTH9, Q9BTI2, A7E2B4, |
UniProt Related Accession: | Q7KZ85 |
Molecular Weight: | 84,632 Da |
NCBI Full Name: | Transcription elongation factor SPT6 |
NCBI Synonym Full Names: | SPT6 homolog, histone chaperone |
NCBI Official Symbol: | SUPT6H |
NCBI Official Synonym Symbols: | SPT6; SPT6H; emb-5 |
NCBI Protein Information: | transcription elongation factor SPT6 |
UniProt Protein Name: | Transcription elongation factor SPT6 |
UniProt Synonym Protein Names: | Histone chaperone suppressor of Ty6; Tat-cotransactivator 2 protein; Tat-CT2 protein |
UniProt Gene Name: | SUPT6H |
UniProt Entry Name: | SPT6H_HUMAN |
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