Anti-SUGCT Antibody (CAB3499)

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SKU:
CAB3499
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-SUGCT Antibody
抗体コード:CAB3499
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IF
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human SUGCT (NP_001180240.1).
申し込み:WB IF
推奨希釈:WB 1:200 - 1:2000 IF 1:50 - 1:200
反応性:Human, Mouse, Rat
ポジティブサンプル:HepG2, Mouse liver, Rat kidney
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human SUGCT (NP_001180240.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:MPSE THAM LATL ARVA ALRR TCLF SGRG GGRG LWTG RPQS DMNN IKPL EGVK ILDL TRVL AGPF ATMN LGDL GAEV IKVE RPGA GDDT RTWG PPFV GTES TYYL SVNR NKKS IAVN IKDP KGVK IIKE LAAV CDVF VENY VPGK LSAM GLGY EDID EIAP HIIY CSIT GYGQ TGPI SQRA GYDA VASA VSGL MHIT GPEN GDPV RPGV AMTD LATG LYAY GAIM AGLI QKYK TGKG LFID CNLL SSQV AC
遺伝子ID:79783
Uniprot:Q9HAC7
セルラーロケーション:Mitochondrion
計算された分子量:43kDa/47kDa/48kDa/51kDa
観察された分子量:48kDa
同義語:SUGCT, C7orf10, DERP13, GA3, ORF19
バックグラウンド:This gene encodes a protein that is similar to members of the CaiB/baiF CoA-transferase protein family. Mutations in this gene are associated with glutaric aciduria type III. Alternate splicing results in multiple transcript variants.
UniProt Protein Function:SUGCT: Defects in C7orf10 are the cause of glutaric aciduria type 3 (GA3). GA3 is a metabolic disorder due to peroxisomal glutaryl-CoA oxidase deficiency and characterized by the excretion of abnormal quantities of glutaric acid but low 3- hydroxyglutaric acid. Belongs to the CaiB/BaiF CoA-transferase family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 2.8.3.13; Transferase

Chromosomal Location of Human Ortholog: 7p14.1

Cellular Component: mitochondrion

Molecular Function:succinate-hydroxymethylglutarate CoA-transferase activity

Biological Process: metabolic process

Disease: Glutaric Aciduria Iii

NCBI Summary:This gene encodes a protein that is similar to members of the CaiB/baiF CoA-transferase protein family. Mutations in this gene are associated with glutaric aciduria type III. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
UniProt Code:Q9HAC7
NCBI GenInfo Identifier:71152390
NCBI Gene ID:79783
NCBI Accession:Q9HAC7.2
UniProt Secondary Accession:Q9HAC7,Q4KMW4, Q4KMW8, Q4KMZ0, Q8TE00, Q8TEY1, A4D1W5 B4DR73,
UniProt Related Accession:Q9HAC7
Molecular Weight:445
NCBI Full Name:Succinate--hydroxymethylglutarate CoA-transferase
NCBI Synonym Full Names:succinyl-CoA:glutarate-CoA transferase
NCBI Official Symbol:SUGCT  
NCBI Official Synonym Symbols:ORF19; DERP13; C7orf10  
NCBI Protein Information:succinate--hydroxymethylglutarate CoA-transferase; Russel-Silver syndrome candidate; dermal papilla-derived protein 13; succinylCoA:glutarate-CoA transferase
UniProt Protein Name:Succinate--hydroxymethylglutarate CoA-transferase
UniProt Synonym Protein Names:Dermal papilla-derived protein 13; SuccinylCoA:glutarate-CoA transferase
Protein Family:Succinate--hydroxymethylglutarate CoA-transferase
UniProt Gene Name:SUGCT  
UniProt Entry Name:SUCHY_HUMAN
Anti-SUGCT Antibody (CAB3499)Western blot analysis of extracts of various cell lines, using SUGCT antibody (CAB3499) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-SUGCT Antibody (CAB3499)Immunofluorescence analysis of U2OS cells using SUGCT antibody (CAB3499) at dilution of 1:100. Blue: DAPI for nuclear staining.
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