Anti-STRN3 Antibody (CAB12586)
- SKU:
- CAB12586
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| 抗体名: | Anti-STRN3 Antibody |
| 抗体コード: | CAB12586 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-460 of human STRN3 (NP_001077362.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-460 of human STRN3 (NP_001077362.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VRSL LGLS NSEP NGSV ETKN LEQI LNGG ESPK QKGQ EIKR SSGD VLET FNFL ENAD DSDE DEEN DMIE GIPE GKDK HRMN KHKI GNEG LAAD LTDD PDTE EALK EFDF LVTA EDGE GAGE ARSS GDGT EWDK DDLS PTAE VWDV DQGL ISKL KEQY KKER KGKK GVKR ANRT KLYD MIAD LGDD ELPH IPSG IINQ SRSA STRM TDHE GARA EEAE PITF PSGG GKSF IMGS DDVL LSVL GLGD LADL TVTN DADY SYDL P |
| 遺伝子ID: | 29966 |
| Uniprot: | Q13033 |
| セルラーロケーション: | Cytoplasm, Membrane, Peripheral membrane protein |
| 計算された分子量: | 77kDa/87kDa |
| 観察された分子量: | 110kDa |
| 同義語: | STRN3, PPP2R6B, S/G2NA, SG2NA |
| バックグラウンド: |
| UniProt Protein Function: | SG2NA: a protein of the WD-repeat striatin family. Mainly expressed within neurons and thought to act both as scaffolds and as Ca(2+)-dependent signalling proteins. May interact with protein phosphatase 2A. Two alternatively spliced isoforms have been described. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Transcription factor; Protein phosphatase, regulatory subunit Chromosomal Location of Human Ortholog: 14q13-q21 Cellular Component: nucleoplasm; Golgi apparatus; protein phosphatase type 2A complex; protein complex; cell soma; cytoplasm; dendrite; plasma membrane; nucleus Molecular Function:calmodulin binding; protein binding; protein phosphatase 2A binding; protein complex binding; transcription factor activity Biological Process: positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; response to estradiol stimulus; negative regulation of estrogen receptor signaling pathway |
| UniProt Code: | Q13033 |
| NCBI GenInfo Identifier: | 223634717 |
| NCBI Gene ID: | 29966 |
| NCBI Accession: | Q13033.3 |
| UniProt Secondary Accession: | Q13033,Q9NRA5, A2RTX7, A6NHZ7, |
| UniProt Related Accession: | Q13033 |
| Molecular Weight: | 797 |
| NCBI Full Name: | Striatin-3 |
| NCBI Synonym Full Names: | striatin, calmodulin binding protein 3 |
| NCBI Official Symbol: | STRN3 |
| NCBI Official Synonym Symbols: | SG2NA |
| NCBI Protein Information: | striatin-3; s/G2 antigen; nuclear autoantigen; cell cycle autoantigen SG2NA; cell cycle S/G2 nuclear autoantigen |
| UniProt Protein Name: | Striatin-3 |
| UniProt Synonym Protein Names: | Cell cycle autoantigen SG2NA; S/G2 antigen |
| Protein Family: | Striatin |
| UniProt Gene Name: | STRN3 |
| UniProt Entry Name: | STRN3_HUMAN |
 | Western blot analysis of extracts of mouse brain, using STRN3 antibody (CAB12586) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunofluorescence analysis of MCF7 cells using STRN3 antibody (CAB12586). Blue: DAPI for nuclear staining. |