Anti-STMN2 Antibody (CAB2997)

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SKU:
CAB2997
Product type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
STMN2
Synonyms:
SCG10
Synonyms:
SCGN10
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Description

抗体名:STMN2 Rabbit pAb
抗体コード:CAB2997
サイズ:100uL
同義語:STMN2, SCG10, SCGN10
申し込み:WB, IHC
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human STMN2 (NP_008960.2).
申し込み:WB, IHC
推奨される希釈:WB 1:500 - 1:1000 IHC 1:50 - 1:100
反応性:Human, Mouse, Rat
ポジティブサンプル:U-87MG
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human STMN2 (NP_008960.2).
精製方法:Affinity purification
保管所:Store at 4°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:11075
Uniprot:Q93045
セルラーロケーション:Cell projection, Cytoplasm, Cytoplasmic side, Endosome, Golgi apparatus, Membrane, Peripheral membrane protein, axon, growth cone, lamellipodium, perinuclear region
計算された分子量:20kDa/21kDa
観察された分子量:25kDa
UniProt Protein Function:STMN2: a cytoskeletal protein that may play a role in neuronal differentiation, and in modulating membrane interaction with the cytoskeleton during neurite outgrowth. Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. Neuron specific.
UniProt Protein Details:

Protein type:Cytoskeletal

Chromosomal Location of Human Ortholog: 8q21.13

Cellular Component: cell soma; cytoplasm; growth cone; lamellipodium; neuron projection; perinuclear region of cytoplasm

Molecular Function:calcium-dependent protein binding; protein binding; tubulin binding

Biological Process: negative regulation of microtubule depolymerization; negative regulation of microtubule polymerization; positive regulation of microtubule depolymerization

NCBI Summary:This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010]
UniProt Code:Q93045
NCBI GenInfo Identifier:51704330
NCBI Gene ID:11075
NCBI Accession:Q93045.3
UniProt Secondary Accession:Q93045,O14952, Q6PK68, A8K9M2, G3V110,
UniProt Related Accession:Q93045
Molecular Weight:21,802 Da
NCBI Full Name:Stathmin-2
NCBI Synonym Full Names:stathmin 2
NCBI Official Symbol:STMN2  
NCBI Official Synonym Symbols:SCG10; SCGN10  
NCBI Protein Information:stathmin-2
UniProt Protein Name:Stathmin-2
UniProt Synonym Protein Names:Superior cervical ganglion-10 protein; Protein SCG10
Protein Family:Stathmin
UniProt Gene Name:STMN2  
UniProt Entry Name:STMN2_HUMAN
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