Anti-STARD4 Antibody (CAB15955)
- SKU:
- CAB15955
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-STARD4 Antibody |
抗体コード: | CAB15955 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human STARD4 (NP_001294986.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse kidney, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human STARD4 (NP_001294986.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MEGL SDVA SFAT KLKN TLIQ YHSI EEDK WRVA KKTK DVTV WRKP SEEF NGYL YKAQ GVID DLVY SIID HIRP GPCR LDWD SLMT SLDI LENF EENC CVMR |
遺伝子ID: | 134429 |
Uniprot: | Q96DR4 |
セルラーロケーション: | |
計算された分子量: | 18kDa/23kDa |
観察された分子量: | 24kDa |
同義語: | STARD4 |
バックグラウンド: | Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]). |
UniProt Protein Function: | STARD4: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 5q22.1 Cellular Component: cytoplasmic membrane-bound vesicle |
NCBI Summary: | Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q96DR4 |
NCBI GenInfo Identifier: | 25091316 |
NCBI Gene ID: | 134429 |
NCBI Accession: | Q96DR4.1 |
UniProt Secondary Accession: | Q96DR4,Q86TN9, |
UniProt Related Accession: | Q96DR4 |
Molecular Weight: | 18,517 Da |
NCBI Full Name: | StAR-related lipid transfer protein 4 |
NCBI Synonym Full Names: | StAR related lipid transfer domain containing 4 |
NCBI Official Symbol: | STARD4 |
NCBI Protein Information: | stAR-related lipid transfer protein 4 |
UniProt Protein Name: | StAR-related lipid transfer protein 4 |
UniProt Synonym Protein Names: | START domain-containing protein 4; StARD4 |
Protein Family: | StAR-related lipid transfer protein |
UniProt Gene Name: | STARD4 |
UniProt Entry Name: | STAR4_HUMAN |
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